A New Case of Schnitzler Syndrome in Bulgaria

We describe the case of a 74-year-old Bulgarian woman with a long history of chronic urticaria with severe burning sensation, arthralgia and fever. Additional symptoms of Schnitzler such as monoclonal immunoglobulin – kappa component, elevated erythrocyte sedimentation rate and enlarged lymph nodes...

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Autores principales:	Kirilova-Doneva M., Kamusheva M., Donev S., Popova I.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2018
Materias:	schnitzler syndrome bulgaria rare disease Medicine R
Acceso en línea:	https://doaj.org/article/c3ab699cdf75485eb593c3fcc747f5f5
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spelling	oai:doaj.org-article:c3ab699cdf75485eb593c3fcc747f5f52021-12-02T14:59:50ZA New Case of Schnitzler Syndrome in Bulgaria0324-175010.2478/amb-2018-0021https://doaj.org/article/c3ab699cdf75485eb593c3fcc747f5f52018-12-01T00:00:00Zhttps://doi.org/10.2478/amb-2018-0021https://doaj.org/toc/0324-1750We describe the case of a 74-year-old Bulgarian woman with a long history of chronic urticaria with severe burning sensation, arthralgia and fever. Additional symptoms of Schnitzler such as monoclonal immunoglobulin – kappa component, elevated erythrocyte sedimentation rate and enlarged lymph nodes were detected six years after the onset of the symptoms. The first diagnoses hypersensitive vasculitis and dermatitis were established in 2009. Schnitzler syndrome was recognized and the diagnosis was established 2 years later after some examination tests. The time course of the values of IgM, C-reactive protein, erythrocyte sedimentation rate and neutrophils were presented. The mean value of IgM is 13.8 ± 2.19 g/l, the mean value of erythrocyte sedimentation rate is 48.6 ± 14.46 mm/h and the mean value of C-reactive protein – 29.8 ± 7.34 mg/l. The use of nonsteroid anti-inflammatory drugs throughout the period and corticosteroids prescribed parenterally and orally resulted in the relief of arthralgia and fever.Kirilova-Doneva M.Kamusheva M.Donev S.Popova I.Sciendoarticleschnitzler syndromebulgariarare diseaseMedicineRENActa Medica Bulgarica, Vol 45, Iss 2, Pp 58-62 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	schnitzler syndrome bulgaria rare disease Medicine R
spellingShingle	schnitzler syndrome bulgaria rare disease Medicine R Kirilova-Doneva M. Kamusheva M. Donev S. Popova I. A New Case of Schnitzler Syndrome in Bulgaria
description	We describe the case of a 74-year-old Bulgarian woman with a long history of chronic urticaria with severe burning sensation, arthralgia and fever. Additional symptoms of Schnitzler such as monoclonal immunoglobulin – kappa component, elevated erythrocyte sedimentation rate and enlarged lymph nodes were detected six years after the onset of the symptoms. The first diagnoses hypersensitive vasculitis and dermatitis were established in 2009. Schnitzler syndrome was recognized and the diagnosis was established 2 years later after some examination tests. The time course of the values of IgM, C-reactive protein, erythrocyte sedimentation rate and neutrophils were presented. The mean value of IgM is 13.8 ± 2.19 g/l, the mean value of erythrocyte sedimentation rate is 48.6 ± 14.46 mm/h and the mean value of C-reactive protein – 29.8 ± 7.34 mg/l. The use of nonsteroid anti-inflammatory drugs throughout the period and corticosteroids prescribed parenterally and orally resulted in the relief of arthralgia and fever.
format	article
author	Kirilova-Doneva M. Kamusheva M. Donev S. Popova I.
author_facet	Kirilova-Doneva M. Kamusheva M. Donev S. Popova I.
author_sort	Kirilova-Doneva M.
title	A New Case of Schnitzler Syndrome in Bulgaria
title_short	A New Case of Schnitzler Syndrome in Bulgaria
title_full	A New Case of Schnitzler Syndrome in Bulgaria
title_fullStr	A New Case of Schnitzler Syndrome in Bulgaria
title_full_unstemmed	A New Case of Schnitzler Syndrome in Bulgaria
title_sort	new case of schnitzler syndrome in bulgaria
publisher	Sciendo
publishDate	2018
url	https://doaj.org/article/c3ab699cdf75485eb593c3fcc747f5f5
work_keys_str_mv	AT kirilovadonevam anewcaseofschnitzlersyndromeinbulgaria AT kamushevam anewcaseofschnitzlersyndromeinbulgaria AT donevs anewcaseofschnitzlersyndromeinbulgaria AT popovai anewcaseofschnitzlersyndromeinbulgaria AT kirilovadonevam newcaseofschnitzlersyndromeinbulgaria AT kamushevam newcaseofschnitzlersyndromeinbulgaria AT donevs newcaseofschnitzlersyndromeinbulgaria AT popovai newcaseofschnitzlersyndromeinbulgaria
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A New Case of Schnitzler Syndrome in Bulgaria

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