Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome

Summary: The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG genes, thus neutralizing the host’s antibody response...

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Autores principales: Alexander Hempelmann, Laura Hartleb, Monique van Straaten, Hamidreza Hashemi, Johan P. Zeelen, Kevin Bongers, F. Nina Papavasiliou, Markus Engstler, C. Erec Stebbins, Nicola G. Jones
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/c3acb4d7657a4e0b8cad190d14971cdf
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