Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease

In order to investigate the role of oligodendrocyte lineage cells in Alzheimer’s Disease (AD) pathology, Nihonmatsu-Kikuchi et al developed a culture method for adult oligodendrocyte progenitor cells in the rat. Using this method as well as imaging AD patient brain tissue, they found that plexin-B3-...

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Autores principales:	Naomi Nihonmatsu-Kikuchi, Xiu-Jun Yu, Yoshiki Matsuda, Nobuyuki Ozawa, Taeko Ito, Kazuhito Satou, Tadashi Kaname, Yasushi Iwasaki, Akio Akagi, Mari Yoshida, Shuta Toru, Katsuiku Hirokawa, Akihiko Takashima, Masato Hasegawa, Toshiki Uchihara, Yoshitaka Tatebayashi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c3ad742aa91b4f32ba2152bb3adc3a06
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spelling	oai:doaj.org-article:c3ad742aa91b4f32ba2152bb3adc3a062021-12-02T15:32:57ZEssential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease10.1038/s42003-021-02404-72399-3642https://doaj.org/article/c3ad742aa91b4f32ba2152bb3adc3a062021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02404-7https://doaj.org/toc/2399-3642In order to investigate the role of oligodendrocyte lineage cells in Alzheimer’s Disease (AD) pathology, Nihonmatsu-Kikuchi et al developed a culture method for adult oligodendrocyte progenitor cells in the rat. Using this method as well as imaging AD patient brain tissue, they found that plexin-B3-expressing cells could be a potential source of amyloid β peptide.Naomi Nihonmatsu-KikuchiXiu-Jun YuYoshiki MatsudaNobuyuki OzawaTaeko ItoKazuhito SatouTadashi KanameYasushi IwasakiAkio AkagiMari YoshidaShuta ToruKatsuiku HirokawaAkihiko TakashimaMasato HasegawaToshiki UchiharaYoshitaka TatebayashiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Naomi Nihonmatsu-Kikuchi Xiu-Jun Yu Yoshiki Matsuda Nobuyuki Ozawa Taeko Ito Kazuhito Satou Tadashi Kaname Yasushi Iwasaki Akio Akagi Mari Yoshida Shuta Toru Katsuiku Hirokawa Akihiko Takashima Masato Hasegawa Toshiki Uchihara Yoshitaka Tatebayashi Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
description	In order to investigate the role of oligodendrocyte lineage cells in Alzheimer’s Disease (AD) pathology, Nihonmatsu-Kikuchi et al developed a culture method for adult oligodendrocyte progenitor cells in the rat. Using this method as well as imaging AD patient brain tissue, they found that plexin-B3-expressing cells could be a potential source of amyloid β peptide.
format	article
author	Naomi Nihonmatsu-Kikuchi Xiu-Jun Yu Yoshiki Matsuda Nobuyuki Ozawa Taeko Ito Kazuhito Satou Tadashi Kaname Yasushi Iwasaki Akio Akagi Mari Yoshida Shuta Toru Katsuiku Hirokawa Akihiko Takashima Masato Hasegawa Toshiki Uchihara Yoshitaka Tatebayashi
author_facet	Naomi Nihonmatsu-Kikuchi Xiu-Jun Yu Yoshiki Matsuda Nobuyuki Ozawa Taeko Ito Kazuhito Satou Tadashi Kaname Yasushi Iwasaki Akio Akagi Mari Yoshida Shuta Toru Katsuiku Hirokawa Akihiko Takashima Masato Hasegawa Toshiki Uchihara Yoshitaka Tatebayashi
author_sort	Naomi Nihonmatsu-Kikuchi
title	Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
title_short	Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
title_full	Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
title_fullStr	Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
title_full_unstemmed	Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
title_sort	essential roles of plexin-b3+ oligodendrocyte precursor cells in the pathogenesis of alzheimer’s disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c3ad742aa91b4f32ba2152bb3adc3a06
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Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease

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