Bypassing stroke-damaged neural pathways via a neural interface induces targeted cortical adaptation

Monkeys were trained to use an artificial cortico-muscular connection (ACMC) to regain control over a paralyzed hand following subcortical stroke. Control over the paralyzed hand was accompanied by the appearance of localized high-gamma modulation in the cortex, which could be rapidly reset and relo...

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Autores principales: Kenji Kato, Masahiro Sawada, Yukio Nishimura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c3ae876ab11343e6a948eeaf054146f8
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Sumario:Monkeys were trained to use an artificial cortico-muscular connection (ACMC) to regain control over a paralyzed hand following subcortical stroke. Control over the paralyzed hand was accompanied by the appearance of localized high-gamma modulation in the cortex, which could be rapidly reset and relocalized to a different cortical site to reactivate motor control.