TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating

Most cells possess sensory cilia, which need to be gated properly. Here the authors show that the C. elegans proteins TALP-3 and ANKR-26 coordinate cilia gating in the context of transition fibers and that this mechanism is conserved in mammalian cells and likely implicated in certain ciliopathies.

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Autores principales:	Hao Yan, Chuan Chen, Huicheng Chen, Hui Hong, Yan Huang, Kun Ling, Jinghua Hu, Qing Wei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c3aefe43facd4d7a9b3f9eb42275c192
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spelling	oai:doaj.org-article:c3aefe43facd4d7a9b3f9eb42275c1922021-12-02T14:42:31ZTALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating10.1038/s41467-020-16042-w2041-1723https://doaj.org/article/c3aefe43facd4d7a9b3f9eb42275c1922020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16042-whttps://doaj.org/toc/2041-1723Most cells possess sensory cilia, which need to be gated properly. Here the authors show that the C. elegans proteins TALP-3 and ANKR-26 coordinate cilia gating in the context of transition fibers and that this mechanism is conserved in mammalian cells and likely implicated in certain ciliopathies.Hao YanChuan ChenHuicheng ChenHui HongYan HuangKun LingJinghua HuQing WeiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hao Yan Chuan Chen Huicheng Chen Hui Hong Yan Huang Kun Ling Jinghua Hu Qing Wei TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
description	Most cells possess sensory cilia, which need to be gated properly. Here the authors show that the C. elegans proteins TALP-3 and ANKR-26 coordinate cilia gating in the context of transition fibers and that this mechanism is conserved in mammalian cells and likely implicated in certain ciliopathies.
format	article
author	Hao Yan Chuan Chen Huicheng Chen Hui Hong Yan Huang Kun Ling Jinghua Hu Qing Wei
author_facet	Hao Yan Chuan Chen Huicheng Chen Hui Hong Yan Huang Kun Ling Jinghua Hu Qing Wei
author_sort	Hao Yan
title	TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
title_short	TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
title_full	TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
title_fullStr	TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
title_full_unstemmed	TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
title_sort	talpid3 and ankrd26 selectively orchestrate fbf1 localization and cilia gating
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c3aefe43facd4d7a9b3f9eb42275c192
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TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating

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