Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products.

Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products.

<h4>Background</h4>Non-enzymatic glycation is the addition of free carbonyl group of reducing sugar to the free amino groups of proteins, resulting in the formation of a Schiff base and an Amadori product. Dihydroxyacetone (DHA) is one of the carbonyl species which reacts rapidly with th...

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Autores principales: Saheem Ahmad, Uzma Shahab, Mohd Hassan Baig, Mohd Sajid Khan, M Salman Khan, A K Srivastava, Mohd Saeed, Moinuddin
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/c3afbd706c0b418d8e83c3b32f50f7b4
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