Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products.
<h4>Background</h4>Non-enzymatic glycation is the addition of free carbonyl group of reducing sugar to the free amino groups of proteins, resulting in the formation of a Schiff base and an Amadori product. Dihydroxyacetone (DHA) is one of the carbonyl species which reacts rapidly with th...
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Subjects: | |
Online Access: | https://doaj.org/article/c3afbd706c0b418d8e83c3b32f50f7b4 |
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