ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling

Abstract Long noncoding RNAs (lncRNAs) are regarded as crucial regulators in tumor progression. Potassium two pore domain channel subfamily K member 15 and WISP2 antisense RNA 1 (KCNK15-AS1) has been confirmed to inhibit the migration and invasion of pancreatic cancer (PC) cells. However, its downst...

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Auteurs principaux: Yuan He, HongQin Yue, Ying Cheng, Zhilong Ding, Zhen Xu, Chunyang Lv, Zheng Wang, Jing Wang, Chenglong Yin, Huihui Hao, Chuang Chen
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/c3afd25950f34ac9aebc5e858819a5b0
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