TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via circuits to ventromedial hypothalamus and lateral par...
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Nature Portfolio
2020
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oai:doaj.org-article:c3b04a71789a4beeb8932ec97ffd3c5c2021-12-02T17:32:58ZTrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits10.1038/s41467-020-15537-w2041-1723https://doaj.org/article/c3b04a71789a4beeb8932ec97ffd3c5c2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15537-whttps://doaj.org/toc/2041-1723The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via circuits to ventromedial hypothalamus and lateral parabrachial nucleus.Juan Ji AnClint E. KinneyJi-Wei TanGuey-Ying LiaoEric J. KremerBaoji XuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020) |
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Science Q Juan Ji An Clint E. Kinney Ji-Wei Tan Guey-Ying Liao Eric J. Kremer Baoji Xu TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
description |
The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via circuits to ventromedial hypothalamus and lateral parabrachial nucleus. |
format |
article |
author |
Juan Ji An Clint E. Kinney Ji-Wei Tan Guey-Ying Liao Eric J. Kremer Baoji Xu |
author_facet |
Juan Ji An Clint E. Kinney Ji-Wei Tan Guey-Ying Liao Eric J. Kremer Baoji Xu |
author_sort |
Juan Ji An |
title |
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
title_short |
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
title_full |
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
title_fullStr |
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
title_full_unstemmed |
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
title_sort |
trkb-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/c3b04a71789a4beeb8932ec97ffd3c5c |
work_keys_str_mv |
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1718380147638272000 |