TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits

The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via circuits to ventromedial hypothalamus and lateral par...

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Autores principales: Juan Ji An, Clint E. Kinney, Ji-Wei Tan, Guey-Ying Liao, Eric J. Kremer, Baoji Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c3b04a71789a4beeb8932ec97ffd3c5c
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spelling oai:doaj.org-article:c3b04a71789a4beeb8932ec97ffd3c5c2021-12-02T17:32:58ZTrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits10.1038/s41467-020-15537-w2041-1723https://doaj.org/article/c3b04a71789a4beeb8932ec97ffd3c5c2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15537-whttps://doaj.org/toc/2041-1723The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via circuits to ventromedial hypothalamus and lateral parabrachial nucleus.Juan Ji AnClint E. KinneyJi-Wei TanGuey-Ying LiaoEric J. KremerBaoji XuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Juan Ji An
Clint E. Kinney
Ji-Wei Tan
Guey-Ying Liao
Eric J. Kremer
Baoji Xu
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
description The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via circuits to ventromedial hypothalamus and lateral parabrachial nucleus.
format article
author Juan Ji An
Clint E. Kinney
Ji-Wei Tan
Guey-Ying Liao
Eric J. Kremer
Baoji Xu
author_facet Juan Ji An
Clint E. Kinney
Ji-Wei Tan
Guey-Ying Liao
Eric J. Kremer
Baoji Xu
author_sort Juan Ji An
title TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
title_short TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
title_full TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
title_fullStr TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
title_full_unstemmed TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
title_sort trkb-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c3b04a71789a4beeb8932ec97ffd3c5c
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