c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences

Objective. Olanzapine (OLA), amisulpride (AMI), aripiprazole (ARI), and quetiapine (QUE) belong to antipsychotics, which administration represents still most reliable way for the treatment of schizophrenic and bipolar disorders. The intention of the present study was to explore whether the acute adm...

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Autores principales:	Kiss Alexander, Osacka Jana
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2020
Materias:	c-fos δfosb olanzapine amisulpride aripiprazole quetiapine mild stressors rat Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/c3b0eb2f40ea4f7686865b06641e156d
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spelling	oai:doaj.org-article:c3b0eb2f40ea4f7686865b06641e156d2021-12-02T16:40:25Zc-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences1336-032910.2478/enr-2020-0006https://doaj.org/article/c3b0eb2f40ea4f7686865b06641e156d2020-01-01T00:00:00Zhttps://doi.org/10.2478/enr-2020-0006https://doaj.org/toc/1336-0329Objective. Olanzapine (OLA), amisulpride (AMI), aripiprazole (ARI), and quetiapine (QUE) belong to antipsychotics, which administration represents still most reliable way for the treatment of schizophrenic and bipolar disorders. The intention of the present study was to explore whether the acute administration of a particular antipsychotic, indicated by the presence of c-Fos, will: a) stimulate neurons already activated by a long lasting homogeneous or heterogeneous stress preconditioning, indicated by the FosB/ΔFosB (ΔFosB) expression, or b) have a stimulatory effect only on a not activated, so called silent neurons. The pattern of ΔFosB and c-Fos spatial relationship was investigated in three forebrain structures, including the septal ventrolateral nucleus (seVL), the striatal dorsolateral area (stDL), and the shell of the nucleus accumbens (shell).Kiss AlexanderOsacka JanaSciendoarticlec-fosδfosbolanzapineamisulpridearipiprazolequetiapinemild stressorsratDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 54, Iss 1, Pp 43-52 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	c-fos δfosb olanzapine amisulpride aripiprazole quetiapine mild stressors rat Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	c-fos δfosb olanzapine amisulpride aripiprazole quetiapine mild stressors rat Diseases of the endocrine glands. Clinical endocrinology RC648-665 Kiss Alexander Osacka Jana c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
description	Objective. Olanzapine (OLA), amisulpride (AMI), aripiprazole (ARI), and quetiapine (QUE) belong to antipsychotics, which administration represents still most reliable way for the treatment of schizophrenic and bipolar disorders. The intention of the present study was to explore whether the acute administration of a particular antipsychotic, indicated by the presence of c-Fos, will: a) stimulate neurons already activated by a long lasting homogeneous or heterogeneous stress preconditioning, indicated by the FosB/ΔFosB (ΔFosB) expression, or b) have a stimulatory effect only on a not activated, so called silent neurons. The pattern of ΔFosB and c-Fos spatial relationship was investigated in three forebrain structures, including the septal ventrolateral nucleus (seVL), the striatal dorsolateral area (stDL), and the shell of the nucleus accumbens (shell).
format	article
author	Kiss Alexander Osacka Jana
author_facet	Kiss Alexander Osacka Jana
author_sort	Kiss Alexander
title	c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
title_short	c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
title_full	c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
title_fullStr	c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
title_full_unstemmed	c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
title_sort	c-fos and fosb/δfosb colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences
publisher	Sciendo
publishDate	2020
url	https://doaj.org/article/c3b0eb2f40ea4f7686865b06641e156d
work_keys_str_mv	AT kissalexander cfosandfosbdfosbcolocalizationsinselectedforebrainstructuresafterolanzapineamisulpridearipiprazoleandquetiapinesingleadministrationinratspreconditionedbytwodifferentmildstressorssequences AT osackajana cfosandfosbdfosbcolocalizationsinselectedforebrainstructuresafterolanzapineamisulpridearipiprazoleandquetiapinesingleadministrationinratspreconditionedbytwodifferentmildstressorssequences
_version_	1718383599221211136

c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences

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