The cryo-EM structure of a γ-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems

The cryo-EM structure of a γ-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems

The nucleation of microtubules from αβ-tubulin subunits is mediated by γtubulin complexes, which vary in composition across organisms. Here, authors present the cryo-EM structure of the heterotetrameric γ-tubulin small complex (γ-TuSC) from C. albicans at near-atomic resolution.

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Autores principales: Erik Zupa, Anjun Zheng, Annett Neuner, Martin Würtz, Peng Liu, Anna Böhler, Elmar Schiebel, Stefan Pfeffer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/c3b177b1e448457da20ea32c914c464f
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