Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression
Chromatin structure plays a significant role in the regulation of gene expression. Here the authors show that TFIIH interacts with the histone acetyl transferase KAT2A and recruits the ATAC/hSAGA complexes to chromatin; and that loss of xeroderma pigmentosum group B (XPB) function results in chromat...
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Auteurs principaux: | Jérémy Sandoz, Zita Nagy, Philippe Catez, Gizem Caliskan, Sylvain Geny, Jean-Baptiste Renaud, Jean-Paul Concordet, Arnaud Poterszman, Laszlo Tora, Jean-Marc Egly, Nicolas Le May, Frédéric Coin |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/c3b2c0ec8f5b4543bcc98340f8ba7994 |
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