Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema

Abstract This study aimed to assess detection rate of telangiectatic capillaries (TelCaps) with infrared reflectance (IR) and optical coherence tomography (OCT) images and to evaluate the clinical efficacy of IR image-guided focal laser photocoagulation of TelCaps in persistent diabetic macular edem...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hyeon Cheol Roh, Chaeyeon Lee, Se Woong Kang, Kyung Jun Choi, Jun Soo Eun, Sungsoon Hwang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c3b5330104304d98b6e5855682768f0c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c3b5330104304d98b6e5855682768f0c
record_format	dspace
spelling	oai:doaj.org-article:c3b5330104304d98b6e5855682768f0c2021-11-08T10:55:41ZInfrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema10.1038/s41598-021-01183-92045-2322https://doaj.org/article/c3b5330104304d98b6e5855682768f0c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01183-9https://doaj.org/toc/2045-2322Abstract This study aimed to assess detection rate of telangiectatic capillaries (TelCaps) with infrared reflectance (IR) and optical coherence tomography (OCT) images and to evaluate the clinical efficacy of IR image-guided focal laser photocoagulation of TelCaps in persistent diabetic macular edema (DME). This retrospective case series included 28 eyes of 28 patients with TelCap and persistent DME refractory to intravitreal anti-vascular endothelial growth factor or corticosteroids. The presence of TelCaps was confirmed using IR and OCT images. All patients were followed up for more than 12 months after direct focal laser photocoagulation of the TelCaps. The TelCap closure rate, changes in best-corrected visual acuity, and central subfield thickness were analyzed. On IR imaging, TelCap appeared as a characteristic hyperreflectivity within a hyporeflective spherical lesion in 85.7% of the eyes. After focal laser photocoagulation, the TelCap closure rate was 57.1% at 3 months and 71.4% at 12 months. A significant improvement in visual acuity and reduction in central subfield thickness were observed at three and 12 months after focal laser photocoagulation (all p < 0.05). The characteristic hyperreflectivity within hyporeflective lesions on the IR image in conjunction with OCT helps identify the TelCap. Our results suggest that IR imaging and OCT-guided focal laser photocoagulation of TelCaps can improve functional and anatomical outcomes in persistent DME.Hyeon Cheol RohChaeyeon LeeSe Woong KangKyung Jun ChoiJun Soo EunSungsoon HwangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hyeon Cheol Roh Chaeyeon Lee Se Woong Kang Kyung Jun Choi Jun Soo Eun Sungsoon Hwang Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
description	Abstract This study aimed to assess detection rate of telangiectatic capillaries (TelCaps) with infrared reflectance (IR) and optical coherence tomography (OCT) images and to evaluate the clinical efficacy of IR image-guided focal laser photocoagulation of TelCaps in persistent diabetic macular edema (DME). This retrospective case series included 28 eyes of 28 patients with TelCap and persistent DME refractory to intravitreal anti-vascular endothelial growth factor or corticosteroids. The presence of TelCaps was confirmed using IR and OCT images. All patients were followed up for more than 12 months after direct focal laser photocoagulation of the TelCaps. The TelCap closure rate, changes in best-corrected visual acuity, and central subfield thickness were analyzed. On IR imaging, TelCap appeared as a characteristic hyperreflectivity within a hyporeflective spherical lesion in 85.7% of the eyes. After focal laser photocoagulation, the TelCap closure rate was 57.1% at 3 months and 71.4% at 12 months. A significant improvement in visual acuity and reduction in central subfield thickness were observed at three and 12 months after focal laser photocoagulation (all p < 0.05). The characteristic hyperreflectivity within hyporeflective lesions on the IR image in conjunction with OCT helps identify the TelCap. Our results suggest that IR imaging and OCT-guided focal laser photocoagulation of TelCaps can improve functional and anatomical outcomes in persistent DME.
format	article
author	Hyeon Cheol Roh Chaeyeon Lee Se Woong Kang Kyung Jun Choi Jun Soo Eun Sungsoon Hwang
author_facet	Hyeon Cheol Roh Chaeyeon Lee Se Woong Kang Kyung Jun Choi Jun Soo Eun Sungsoon Hwang
author_sort	Hyeon Cheol Roh
title	Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
title_short	Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
title_full	Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
title_fullStr	Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
title_full_unstemmed	Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
title_sort	infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c3b5330104304d98b6e5855682768f0c
work_keys_str_mv	AT hyeoncheolroh infraredreflectanceimageguidedlaserphotocoagulationoftelangiectaticcapillariesinpersistentdiabeticmacularedema AT chaeyeonlee infraredreflectanceimageguidedlaserphotocoagulationoftelangiectaticcapillariesinpersistentdiabeticmacularedema AT sewoongkang infraredreflectanceimageguidedlaserphotocoagulationoftelangiectaticcapillariesinpersistentdiabeticmacularedema AT kyungjunchoi infraredreflectanceimageguidedlaserphotocoagulationoftelangiectaticcapillariesinpersistentdiabeticmacularedema AT junsooeun infraredreflectanceimageguidedlaserphotocoagulationoftelangiectaticcapillariesinpersistentdiabeticmacularedema AT sungsoonhwang infraredreflectanceimageguidedlaserphotocoagulationoftelangiectaticcapillariesinpersistentdiabeticmacularedema
_version_	1718442564235821056

Infrared reflectance image-guided laser photocoagulation of telangiectatic capillaries in persistent diabetic macular edema

Ejemplares similares