An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content>

An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content>

ABSTRACT Biosynthesis of many ecologically important secondary metabolites (SMs) in filamentous fungi is controlled by several global transcriptional regulators, like the chromatin modifier LaeA, and tied to both development and vegetative growth. In Aspergillus molds, asexual development is regulat...

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Autores principales: Abigail L. Lind, Fang Yun Lim, Alexandra A. Soukup, Nancy P. Keller, Antonis Rokas
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
biosynthetic gene cluster
conidia
hyphal growth
hypoxia
mycelial growth
specialized metabolism
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/c3becbac9eef416aa30704f486e1ae60
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