Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration

Directed motility of cell clusters requires coordination of protrusion formation at the front of leader cells and contractility at the rear. Here the authors show that the kinase Misshapen restricts protrusions to the leader cell and promotes contractile forces at the rear of the cluster.

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Autores principales:	Cédric Plutoni, Sarah Keil, Carlos Zeledon, Lara Elis Alberici Delsin, Barbara Decelle, Philippe P. Roux, Sébastien Carréno, Gregory Emery
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c3bf05a570ba4232b76b6c36ab987f6c
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spelling	oai:doaj.org-article:c3bf05a570ba4232b76b6c36ab987f6c2021-12-02T16:58:01ZMisshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration10.1038/s41467-019-11963-72041-1723https://doaj.org/article/c3bf05a570ba4232b76b6c36ab987f6c2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11963-7https://doaj.org/toc/2041-1723Directed motility of cell clusters requires coordination of protrusion formation at the front of leader cells and contractility at the rear. Here the authors show that the kinase Misshapen restricts protrusions to the leader cell and promotes contractile forces at the rear of the cluster.Cédric PlutoniSarah KeilCarlos ZeledonLara Elis Alberici DelsinBarbara DecellePhilippe P. RouxSébastien CarrénoGregory EmeryNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cédric Plutoni Sarah Keil Carlos Zeledon Lara Elis Alberici Delsin Barbara Decelle Philippe P. Roux Sébastien Carréno Gregory Emery Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
description	Directed motility of cell clusters requires coordination of protrusion formation at the front of leader cells and contractility at the rear. Here the authors show that the kinase Misshapen restricts protrusions to the leader cell and promotes contractile forces at the rear of the cluster.
format	article
author	Cédric Plutoni Sarah Keil Carlos Zeledon Lara Elis Alberici Delsin Barbara Decelle Philippe P. Roux Sébastien Carréno Gregory Emery
author_facet	Cédric Plutoni Sarah Keil Carlos Zeledon Lara Elis Alberici Delsin Barbara Decelle Philippe P. Roux Sébastien Carréno Gregory Emery
author_sort	Cédric Plutoni
title	Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
title_short	Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
title_full	Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
title_fullStr	Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
title_full_unstemmed	Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
title_sort	misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c3bf05a570ba4232b76b6c36ab987f6c
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Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration

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