Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma

Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here the authors show that the molecular alterations and heterogeneity of paediatric medulloblastomas can be reliably detected in circulating tumour DNA from the cerebrospinal fluid – a routinely collected sample....

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Autores principales:	Laura Escudero, Anna Llort, Alexandra Arias, Ander Diaz-Navarro, Francisco Martínez-Ricarte, Carlota Rubio-Perez, Regina Mayor, Ginevra Caratù, Elena Martínez-Sáez, Élida Vázquez-Méndez, Iván Lesende-Rodríguez, Raquel Hladun, Luis Gros, Santiago Ramón y Cajal, Maria A. Poca, Xose S. Puente, Juan Sahuquillo, Soledad Gallego, Joan Seoane
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c3bf556831fd4765979786b61390d38a
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spelling	oai:doaj.org-article:c3bf556831fd4765979786b61390d38a2021-12-02T14:40:28ZCirculating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma10.1038/s41467-020-19175-02041-1723https://doaj.org/article/c3bf556831fd4765979786b61390d38a2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19175-0https://doaj.org/toc/2041-1723Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here the authors show that the molecular alterations and heterogeneity of paediatric medulloblastomas can be reliably detected in circulating tumour DNA from the cerebrospinal fluid – a routinely collected sample.Laura EscuderoAnna LlortAlexandra AriasAnder Diaz-NavarroFrancisco Martínez-RicarteCarlota Rubio-PerezRegina MayorGinevra CaratùElena Martínez-SáezÉlida Vázquez-MéndezIván Lesende-RodríguezRaquel HladunLuis GrosSantiago Ramón y CajalMaria A. PocaXose S. PuenteJuan SahuquilloSoledad GallegoJoan SeoaneNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laura Escudero Anna Llort Alexandra Arias Ander Diaz-Navarro Francisco Martínez-Ricarte Carlota Rubio-Perez Regina Mayor Ginevra Caratù Elena Martínez-Sáez Élida Vázquez-Méndez Iván Lesende-Rodríguez Raquel Hladun Luis Gros Santiago Ramón y Cajal Maria A. Poca Xose S. Puente Juan Sahuquillo Soledad Gallego Joan Seoane Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
description	Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here the authors show that the molecular alterations and heterogeneity of paediatric medulloblastomas can be reliably detected in circulating tumour DNA from the cerebrospinal fluid – a routinely collected sample.
format	article
author	Laura Escudero Anna Llort Alexandra Arias Ander Diaz-Navarro Francisco Martínez-Ricarte Carlota Rubio-Perez Regina Mayor Ginevra Caratù Elena Martínez-Sáez Élida Vázquez-Méndez Iván Lesende-Rodríguez Raquel Hladun Luis Gros Santiago Ramón y Cajal Maria A. Poca Xose S. Puente Juan Sahuquillo Soledad Gallego Joan Seoane
author_facet	Laura Escudero Anna Llort Alexandra Arias Ander Diaz-Navarro Francisco Martínez-Ricarte Carlota Rubio-Perez Regina Mayor Ginevra Caratù Elena Martínez-Sáez Élida Vázquez-Méndez Iván Lesende-Rodríguez Raquel Hladun Luis Gros Santiago Ramón y Cajal Maria A. Poca Xose S. Puente Juan Sahuquillo Soledad Gallego Joan Seoane
author_sort	Laura Escudero
title	Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
title_short	Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
title_full	Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
title_fullStr	Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
title_full_unstemmed	Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
title_sort	circulating tumour dna from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c3bf556831fd4765979786b61390d38a
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Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma

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