HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER

Objective: To assess and compare the frequency of haematological parameter derangements in patients due to non-resistant and extended drug resistant (XDR) typhoid fever. Study Design: Comparative cross-sectional study. Place and Duration of Study: Pathology Department of Combined Military Hosp...

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Autores principales:	Sunila Tashfeen, Naveed Asif, Muhammad Farooq
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	extended drug resistant typhoid haematological parameters Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c3c03ca2411849af875b84ac365344c5
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spelling	oai:doaj.org-article:c3c03ca2411849af875b84ac365344c52021-11-18T04:22:40ZHAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER0030-96482411-8842https://doaj.org/article/c3c03ca2411849af875b84ac365344c52021-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/4359/3586https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess and compare the frequency of haematological parameter derangements in patients due to non-resistant and extended drug resistant (XDR) typhoid fever. Study Design: Comparative cross-sectional study. Place and Duration of Study: Pathology Department of Combined Military Hospital Quetta, from Jan to Dec 2019. Methodology: A total number of 172 blood culture Salmonella positive patients irrespective of age and gender were included in this study. Salmonella strains were isolated and grouped further according to their drugs sensitivity. 3ml venous blood was collected from these patients in Ethylene diamine tetra acetic acid container and blood complete count was done by semiautomated haematology analyser XP-100. Results: There were 126 (73%) males and 46 (27%) females with mean age of 17.5 ± 10.3 years. Out of 172 subjects, 106 (61.6%) had non-resistant typhoid and rest 66 (38.4%) were diagnosed with extended drug resistant Typhoid. We compared anaemia, leucopenia and thrombocytopenia between two groups and found anaemia statistically significant with the p-value of 0.001. Conclusion: This study has documented that changes in haematological parameters are significant in typhoid fever and early patients diagnosis, management and disease course can be monitored with them. Patients with significant anaemia and not responding to first line therapy should be considered as a case of extended drug resistant (XDR) Salmonella.Sunila TashfeenNaveed AsifMuhammad FarooqArmy Medical College Rawalpindiarticleextended drug resistant typhoidhaematological parametersMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 5, Pp 1615-1618 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	extended drug resistant typhoid haematological parameters Medicine R Medicine (General) R5-920
spellingShingle	extended drug resistant typhoid haematological parameters Medicine R Medicine (General) R5-920 Sunila Tashfeen Naveed Asif Muhammad Farooq HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER
description	Objective: To assess and compare the frequency of haematological parameter derangements in patients due to non-resistant and extended drug resistant (XDR) typhoid fever. Study Design: Comparative cross-sectional study. Place and Duration of Study: Pathology Department of Combined Military Hospital Quetta, from Jan to Dec 2019. Methodology: A total number of 172 blood culture Salmonella positive patients irrespective of age and gender were included in this study. Salmonella strains were isolated and grouped further according to their drugs sensitivity. 3ml venous blood was collected from these patients in Ethylene diamine tetra acetic acid container and blood complete count was done by semiautomated haematology analyser XP-100. Results: There were 126 (73%) males and 46 (27%) females with mean age of 17.5 ± 10.3 years. Out of 172 subjects, 106 (61.6%) had non-resistant typhoid and rest 66 (38.4%) were diagnosed with extended drug resistant Typhoid. We compared anaemia, leucopenia and thrombocytopenia between two groups and found anaemia statistically significant with the p-value of 0.001. Conclusion: This study has documented that changes in haematological parameters are significant in typhoid fever and early patients diagnosis, management and disease course can be monitored with them. Patients with significant anaemia and not responding to first line therapy should be considered as a case of extended drug resistant (XDR) Salmonella.
format	article
author	Sunila Tashfeen Naveed Asif Muhammad Farooq
author_facet	Sunila Tashfeen Naveed Asif Muhammad Farooq
author_sort	Sunila Tashfeen
title	HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER
title_short	HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER
title_full	HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER
title_fullStr	HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER
title_full_unstemmed	HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER
title_sort	haematological profile derangements in patients due to non-resistant and resistant typhoid fever
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/c3c03ca2411849af875b84ac365344c5
work_keys_str_mv	AT sunilatashfeen haematologicalprofilederangementsinpatientsduetononresistantandresistanttyphoidfever AT naveedasif haematologicalprofilederangementsinpatientsduetononresistantandresistanttyphoidfever AT muhammadfarooq haematologicalprofilederangementsinpatientsduetononresistantandresistanttyphoidfever
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HAEMATOLOGICAL PROFILE DERANGEMENTS IN PATIENTS DUE TO NON-RESISTANT AND RESISTANT TYPHOID FEVER

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