Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis

Centromeres are the sites of kinetochore and inner centromere formation, which can be epigenetically regulated. Here, the authors reveal a role for the lymphocyte specific helicase LSH/Hells associated with pericentric heterochromatin formation in centromere stability and chromosome segregation at m...

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Main Authors:	Claudia Baumann, Wei Ma, Xiaotian Wang, Muthugapatti K. Kandasamy, Maria M. Viveiros, Rabindranath De La Fuente
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/c3cbd3e96cf44ad4bd3f3ff48818c972
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spelling	oai:doaj.org-article:c3cbd3e96cf44ad4bd3f3ff48818c9722021-12-02T18:03:07ZHelicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis10.1038/s41467-020-18009-32041-1723https://doaj.org/article/c3cbd3e96cf44ad4bd3f3ff48818c9722020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18009-3https://doaj.org/toc/2041-1723Centromeres are the sites of kinetochore and inner centromere formation, which can be epigenetically regulated. Here, the authors reveal a role for the lymphocyte specific helicase LSH/Hells associated with pericentric heterochromatin formation in centromere stability and chromosome segregation at meiotic kinetochores.Claudia BaumannWei MaXiaotian WangMuthugapatti K. KandasamyMaria M. ViveirosRabindranath De La FuenteNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Claudia Baumann Wei Ma Xiaotian Wang Muthugapatti K. Kandasamy Maria M. Viveiros Rabindranath De La Fuente Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
description	Centromeres are the sites of kinetochore and inner centromere formation, which can be epigenetically regulated. Here, the authors reveal a role for the lymphocyte specific helicase LSH/Hells associated with pericentric heterochromatin formation in centromere stability and chromosome segregation at meiotic kinetochores.
format	article
author	Claudia Baumann Wei Ma Xiaotian Wang Muthugapatti K. Kandasamy Maria M. Viveiros Rabindranath De La Fuente
author_facet	Claudia Baumann Wei Ma Xiaotian Wang Muthugapatti K. Kandasamy Maria M. Viveiros Rabindranath De La Fuente
author_sort	Claudia Baumann
title	Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
title_short	Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
title_full	Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
title_fullStr	Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
title_full_unstemmed	Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
title_sort	helicase lsh/hells regulates kinetochore function, histone h3/thr3 phosphorylation and centromere transcription during oocyte meiosis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c3cbd3e96cf44ad4bd3f3ff48818c972
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Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis

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