Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis

Centromeres are the sites of kinetochore and inner centromere formation, which can be epigenetically regulated. Here, the authors reveal a role for the lymphocyte specific helicase LSH/Hells associated with pericentric heterochromatin formation in centromere stability and chromosome segregation at m...

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Autores principales: Claudia Baumann, Wei Ma, Xiaotian Wang, Muthugapatti K. Kandasamy, Maria M. Viveiros, Rabindranath De La Fuente
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c3cbd3e96cf44ad4bd3f3ff48818c972
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