Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)

Immune cells are important regulators of adipose tissue function, including adaptive thermogenesis. Here the authors show that mice with Krüppel-like factor 3 (KLF3) deficiency in bone marrow-derived cells have increased adipose tissue beiging which may at least in part be due to altered eosinophil...

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Autores principales: Alexander J. Knights, Emily J. Vohralik, Peter J. Houweling, Elizabeth S. Stout, Laura J. Norton, Stephanie J. Alexopoulos, Jinfen. J. Yik, Hanapi Mat Jusoh, Ellen M. Olzomer, Kim S. Bell-Anderson, Kathryn N. North, Kyle L. Hoehn, Merlin Crossley, Kate G. R. Quinlan
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c3cf746046c44c4288224f72b4e3c524
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spelling oai:doaj.org-article:c3cf746046c44c4288224f72b4e3c5242021-12-02T17:47:34ZEosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)10.1038/s41467-020-16758-92041-1723https://doaj.org/article/c3cf746046c44c4288224f72b4e3c5242020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16758-9https://doaj.org/toc/2041-1723Immune cells are important regulators of adipose tissue function, including adaptive thermogenesis. Here the authors show that mice with Krüppel-like factor 3 (KLF3) deficiency in bone marrow-derived cells have increased adipose tissue beiging which may at least in part be due to altered eosinophil paracrine signaling.Alexander J. KnightsEmily J. VohralikPeter J. HouwelingElizabeth S. StoutLaura J. NortonStephanie J. AlexopoulosJinfen. J. YikHanapi Mat JusohEllen M. OlzomerKim S. Bell-AndersonKathryn N. NorthKyle L. HoehnMerlin CrossleyKate G. R. QuinlanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander J. Knights
Emily J. Vohralik
Peter J. Houweling
Elizabeth S. Stout
Laura J. Norton
Stephanie J. Alexopoulos
Jinfen. J. Yik
Hanapi Mat Jusoh
Ellen M. Olzomer
Kim S. Bell-Anderson
Kathryn N. North
Kyle L. Hoehn
Merlin Crossley
Kate G. R. Quinlan
Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
description Immune cells are important regulators of adipose tissue function, including adaptive thermogenesis. Here the authors show that mice with Krüppel-like factor 3 (KLF3) deficiency in bone marrow-derived cells have increased adipose tissue beiging which may at least in part be due to altered eosinophil paracrine signaling.
format article
author Alexander J. Knights
Emily J. Vohralik
Peter J. Houweling
Elizabeth S. Stout
Laura J. Norton
Stephanie J. Alexopoulos
Jinfen. J. Yik
Hanapi Mat Jusoh
Ellen M. Olzomer
Kim S. Bell-Anderson
Kathryn N. North
Kyle L. Hoehn
Merlin Crossley
Kate G. R. Quinlan
author_facet Alexander J. Knights
Emily J. Vohralik
Peter J. Houweling
Elizabeth S. Stout
Laura J. Norton
Stephanie J. Alexopoulos
Jinfen. J. Yik
Hanapi Mat Jusoh
Ellen M. Olzomer
Kim S. Bell-Anderson
Kathryn N. North
Kyle L. Hoehn
Merlin Crossley
Kate G. R. Quinlan
author_sort Alexander J. Knights
title Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
title_short Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
title_full Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
title_fullStr Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
title_full_unstemmed Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
title_sort eosinophil function in adipose tissue is regulated by krüppel-like factor 3 (klf3)
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c3cf746046c44c4288224f72b4e3c524
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