Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

Previous genome-wide association studies have identified loci associated with the risk of multiple myeloma. Here, the authors present a meta-analysis of six genome wide association studies of the disease and identify eight new loci; functional studies identify genes as candidates for the basis of th...

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Autores principales:	Jonathan S. Mitchell, Ni Li, Niels Weinhold, Asta Försti, Mina Ali, Mark van Duin, Gudmar Thorleifsson, David C. Johnson, Bowang Chen, Britt-Marie Halvarsson, Daniel F. Gudbjartsson, Rowan Kuiper, Owen W. Stephens, Uta Bertsch, Peter Broderick, Chiara Campo, Hermann Einsele, Walter A. Gregory, Urban Gullberg, Marc Henrion, Jens Hillengass, Per Hoffmann, Graham H. Jackson, Ellinor Johnsson, Magnus Jöud, Sigurður Y. Kristinsson, Stig Lenhoff, Oleg Lenive, Ulf-Henrik Mellqvist, Gabriele Migliorini, Hareth Nahi, Sven Nelander, Jolanta Nickel, Markus M. Nöthen, Thorunn Rafnar, Fiona M. Ross, Miguel Inacio da Silva Filho, Bhairavi Swaminathan, Hauke Thomsen, Ingemar Turesson, Annette Vangsted, Ulla Vogel, Anders Waage, Brian A. Walker, Anna-Karin Wihlborg, Annemiek Broyl, Faith E. Davies, Unnur Thorsteinsdottir, Christian Langer, Markus Hansson, Martin Kaiser, Pieter Sonneveld, Kari Stefansson, Gareth J. Morgan, Hartmut Goldschmidt, Kari Hemminki, Björn Nilsson, Richard S. Houlston
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c3cfde00727b4a92a967fbff352be77c
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spelling	oai:doaj.org-article:c3cfde00727b4a92a967fbff352be77c2021-12-02T16:50:15ZGenome-wide association study identifies multiple susceptibility loci for multiple myeloma10.1038/ncomms120502041-1723https://doaj.org/article/c3cfde00727b4a92a967fbff352be77c2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12050https://doaj.org/toc/2041-1723Previous genome-wide association studies have identified loci associated with the risk of multiple myeloma. Here, the authors present a meta-analysis of six genome wide association studies of the disease and identify eight new loci; functional studies identify genes as candidates for the basis of these associations.Jonathan S. MitchellNi LiNiels WeinholdAsta FörstiMina AliMark van DuinGudmar ThorleifssonDavid C. JohnsonBowang ChenBritt-Marie HalvarssonDaniel F. GudbjartssonRowan KuiperOwen W. StephensUta BertschPeter BroderickChiara CampoHermann EinseleWalter A. GregoryUrban GullbergMarc HenrionJens HillengassPer HoffmannGraham H. JacksonEllinor JohnssonMagnus JöudSigurður Y. KristinssonStig LenhoffOleg LeniveUlf-Henrik MellqvistGabriele MiglioriniHareth NahiSven NelanderJolanta NickelMarkus M. NöthenThorunn RafnarFiona M. RossMiguel Inacio da Silva FilhoBhairavi SwaminathanHauke ThomsenIngemar TuressonAnnette VangstedUlla VogelAnders WaageBrian A. WalkerAnna-Karin WihlborgAnnemiek BroylFaith E. DaviesUnnur ThorsteinsdottirChristian LangerMarkus HanssonMartin KaiserPieter SonneveldKari StefanssonGareth J. MorganHartmut GoldschmidtKari HemminkiBjörn NilssonRichard S. HoulstonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jonathan S. Mitchell Ni Li Niels Weinhold Asta Försti Mina Ali Mark van Duin Gudmar Thorleifsson David C. Johnson Bowang Chen Britt-Marie Halvarsson Daniel F. Gudbjartsson Rowan Kuiper Owen W. Stephens Uta Bertsch Peter Broderick Chiara Campo Hermann Einsele Walter A. Gregory Urban Gullberg Marc Henrion Jens Hillengass Per Hoffmann Graham H. Jackson Ellinor Johnsson Magnus Jöud Sigurður Y. Kristinsson Stig Lenhoff Oleg Lenive Ulf-Henrik Mellqvist Gabriele Migliorini Hareth Nahi Sven Nelander Jolanta Nickel Markus M. Nöthen Thorunn Rafnar Fiona M. Ross Miguel Inacio da Silva Filho Bhairavi Swaminathan Hauke Thomsen Ingemar Turesson Annette Vangsted Ulla Vogel Anders Waage Brian A. Walker Anna-Karin Wihlborg Annemiek Broyl Faith E. Davies Unnur Thorsteinsdottir Christian Langer Markus Hansson Martin Kaiser Pieter Sonneveld Kari Stefansson Gareth J. Morgan Hartmut Goldschmidt Kari Hemminki Björn Nilsson Richard S. Houlston Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
description	Previous genome-wide association studies have identified loci associated with the risk of multiple myeloma. Here, the authors present a meta-analysis of six genome wide association studies of the disease and identify eight new loci; functional studies identify genes as candidates for the basis of these associations.
format	article
author	Jonathan S. Mitchell Ni Li Niels Weinhold Asta Försti Mina Ali Mark van Duin Gudmar Thorleifsson David C. Johnson Bowang Chen Britt-Marie Halvarsson Daniel F. Gudbjartsson Rowan Kuiper Owen W. Stephens Uta Bertsch Peter Broderick Chiara Campo Hermann Einsele Walter A. Gregory Urban Gullberg Marc Henrion Jens Hillengass Per Hoffmann Graham H. Jackson Ellinor Johnsson Magnus Jöud Sigurður Y. Kristinsson Stig Lenhoff Oleg Lenive Ulf-Henrik Mellqvist Gabriele Migliorini Hareth Nahi Sven Nelander Jolanta Nickel Markus M. Nöthen Thorunn Rafnar Fiona M. Ross Miguel Inacio da Silva Filho Bhairavi Swaminathan Hauke Thomsen Ingemar Turesson Annette Vangsted Ulla Vogel Anders Waage Brian A. Walker Anna-Karin Wihlborg Annemiek Broyl Faith E. Davies Unnur Thorsteinsdottir Christian Langer Markus Hansson Martin Kaiser Pieter Sonneveld Kari Stefansson Gareth J. Morgan Hartmut Goldschmidt Kari Hemminki Björn Nilsson Richard S. Houlston
author_facet	Jonathan S. Mitchell Ni Li Niels Weinhold Asta Försti Mina Ali Mark van Duin Gudmar Thorleifsson David C. Johnson Bowang Chen Britt-Marie Halvarsson Daniel F. Gudbjartsson Rowan Kuiper Owen W. Stephens Uta Bertsch Peter Broderick Chiara Campo Hermann Einsele Walter A. Gregory Urban Gullberg Marc Henrion Jens Hillengass Per Hoffmann Graham H. Jackson Ellinor Johnsson Magnus Jöud Sigurður Y. Kristinsson Stig Lenhoff Oleg Lenive Ulf-Henrik Mellqvist Gabriele Migliorini Hareth Nahi Sven Nelander Jolanta Nickel Markus M. Nöthen Thorunn Rafnar Fiona M. Ross Miguel Inacio da Silva Filho Bhairavi Swaminathan Hauke Thomsen Ingemar Turesson Annette Vangsted Ulla Vogel Anders Waage Brian A. Walker Anna-Karin Wihlborg Annemiek Broyl Faith E. Davies Unnur Thorsteinsdottir Christian Langer Markus Hansson Martin Kaiser Pieter Sonneveld Kari Stefansson Gareth J. Morgan Hartmut Goldschmidt Kari Hemminki Björn Nilsson Richard S. Houlston
author_sort	Jonathan S. Mitchell
title	Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
title_short	Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
title_full	Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
title_fullStr	Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
title_full_unstemmed	Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
title_sort	genome-wide association study identifies multiple susceptibility loci for multiple myeloma
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c3cfde00727b4a92a967fbff352be77c
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Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

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