Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.

We investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health scree...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tae-Jin Song, Yoonkyung Chang, Jimin Jeon, Jinkwon Kim
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c3d6eb9cd1bd40e78e9f78c7ed7adf34
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c3d6eb9cd1bd40e78e9f78c7ed7adf34
record_format	dspace
spelling	oai:doaj.org-article:c3d6eb9cd1bd40e78e9f78c7ed7adf342021-12-02T20:09:50ZOral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.1932-620310.1371/journal.pone.0253769https://doaj.org/article/c3d6eb9cd1bd40e78e9f78c7ed7adf342021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253769https://doaj.org/toc/1932-6203We investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health screening program with oral health check in 2009-2010. We constructed a linear mixed model for the longitudinal data of fasting glucose from the baseline to 2015. During the 4.84-year of median follow-up, 91,963 individuals (mean age 56.2 at baseline) underwent 392,780 health examinations with fasting glucose level (mmol/L). The presence of periodontitis was 39.3%. In the multivariate linear mixed analysis, periodontitis was related with increased fasting glucose levels (β = 0.0084, standard error = 0.0035, p = 0.018). Similarly, tooth loss was associated with increased level of fasting glucose (β = 0.0246, standard error = 0.0038, p < 0.001). Compared with tooth brushing ≤2 times/day, tooth brushing ≥3 times/day was associated with decreased fasting glucose levels (β = -0.0207, standard error = 0.0033, p < 0.001). Our data showed that periodontitis and tooth loss were associated with increased fasting glucose levels in non-diabetic individuals. The study findings imply that frequent tooth brushing may reduce fasting glucose levels. Further research is needed to determine the effect of periodontal intervention on glycemic control.Tae-Jin SongYoonkyung ChangJimin JeonJinkwon KimPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253769 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tae-Jin Song Yoonkyung Chang Jimin Jeon Jinkwon Kim Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
description	We investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health screening program with oral health check in 2009-2010. We constructed a linear mixed model for the longitudinal data of fasting glucose from the baseline to 2015. During the 4.84-year of median follow-up, 91,963 individuals (mean age 56.2 at baseline) underwent 392,780 health examinations with fasting glucose level (mmol/L). The presence of periodontitis was 39.3%. In the multivariate linear mixed analysis, periodontitis was related with increased fasting glucose levels (β = 0.0084, standard error = 0.0035, p = 0.018). Similarly, tooth loss was associated with increased level of fasting glucose (β = 0.0246, standard error = 0.0038, p < 0.001). Compared with tooth brushing ≤2 times/day, tooth brushing ≥3 times/day was associated with decreased fasting glucose levels (β = -0.0207, standard error = 0.0033, p < 0.001). Our data showed that periodontitis and tooth loss were associated with increased fasting glucose levels in non-diabetic individuals. The study findings imply that frequent tooth brushing may reduce fasting glucose levels. Further research is needed to determine the effect of periodontal intervention on glycemic control.
format	article
author	Tae-Jin Song Yoonkyung Chang Jimin Jeon Jinkwon Kim
author_facet	Tae-Jin Song Yoonkyung Chang Jimin Jeon Jinkwon Kim
author_sort	Tae-Jin Song
title	Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
title_short	Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
title_full	Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
title_fullStr	Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
title_full_unstemmed	Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
title_sort	oral health and longitudinal changes in fasting glucose levels: a nationwide cohort study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/c3d6eb9cd1bd40e78e9f78c7ed7adf34
work_keys_str_mv	AT taejinsong oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy AT yoonkyungchang oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy AT jiminjeon oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy AT jinkwonkim oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy
_version_	1718375088635510784

Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.

Ejemplares similares