3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels

Cellular models are needed to study disease in vitro and to screen drugs for toxicity and efficacy. Here the authors develop a bioprinting approach to transfer spheroids into self-healing support hydrogels at high resolution, which enables their patterning and fusion into high-cell density microtiss...

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Autores principales:	Andrew C. Daly, Matthew D. Davidson, Jason A. Burdick
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c3e8be08fce540e59149aea73ed06887
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spelling	oai:doaj.org-article:c3e8be08fce540e59149aea73ed068872021-12-02T10:44:12Z3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels10.1038/s41467-021-21029-22041-1723https://doaj.org/article/c3e8be08fce540e59149aea73ed068872021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21029-2https://doaj.org/toc/2041-1723Cellular models are needed to study disease in vitro and to screen drugs for toxicity and efficacy. Here the authors develop a bioprinting approach to transfer spheroids into self-healing support hydrogels at high resolution, which enables their patterning and fusion into high-cell density microtissues of prescribed spatial organization.Andrew C. DalyMatthew D. DavidsonJason A. BurdickNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrew C. Daly Matthew D. Davidson Jason A. Burdick 3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
description	Cellular models are needed to study disease in vitro and to screen drugs for toxicity and efficacy. Here the authors develop a bioprinting approach to transfer spheroids into self-healing support hydrogels at high resolution, which enables their patterning and fusion into high-cell density microtissues of prescribed spatial organization.
format	article
author	Andrew C. Daly Matthew D. Davidson Jason A. Burdick
author_facet	Andrew C. Daly Matthew D. Davidson Jason A. Burdick
author_sort	Andrew C. Daly
title	3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
title_short	3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
title_full	3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
title_fullStr	3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
title_full_unstemmed	3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
title_sort	3d bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c3e8be08fce540e59149aea73ed06887
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3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels

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