Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness

As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT will lead to obesity. It is worth noting that exercise can reduce the fat mass. There is also a lot of evidence that exe...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wang-Jing Mu, Jie-Ying Zhu, Min Chen, Liang Guo
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	browning of WAT exercise Ucp1 ROS metabolites exerkines Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/c3eb8ac38636443aa406e224e115bf1c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c3eb8ac38636443aa406e224e115bf1c
record_format	dspace
spelling	oai:doaj.org-article:c3eb8ac38636443aa406e224e115bf1c2021-11-11T16:58:27ZExercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness10.3390/ijms2221115121422-00671661-6596https://doaj.org/article/c3eb8ac38636443aa406e224e115bf1c2021-10-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/21/11512https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT will lead to obesity. It is worth noting that exercise can reduce the fat mass. There is also a lot of evidence that exercise can promote the browning of WAT, which is beneficial for metabolic homeostasis. Multiple factors, including reactive oxygen species (ROS), metabolites, nervous system, exerkines and lipolysis can facilitate exercise-mediated browning of WAT. In this review, the roles and the underlying mechanisms of exercise-mediated browning of WAT are summarized. The effects of different styles of exercise on the browning of WAT are also discussed, with the aim to propose better exercise strategies to enhance exercise-mediated browning of WAT, so as to promote metabolic health. Finally, the different reactivity of WAT at different anatomical sites to exercise-mediated browning is reviewed, which may provide potential suggestion for people with different fat loss needs.Wang-Jing MuJie-Ying ZhuMin ChenLiang GuoMDPI AGarticlebrowning of WATexerciseUcp1ROSmetabolitesexerkinesBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 11512, p 11512 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	browning of WAT exercise Ucp1 ROS metabolites exerkines Biology (General) QH301-705.5 Chemistry QD1-999
spellingShingle	browning of WAT exercise Ucp1 ROS metabolites exerkines Biology (General) QH301-705.5 Chemistry QD1-999 Wang-Jing Mu Jie-Ying Zhu Min Chen Liang Guo Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
description	As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT will lead to obesity. It is worth noting that exercise can reduce the fat mass. There is also a lot of evidence that exercise can promote the browning of WAT, which is beneficial for metabolic homeostasis. Multiple factors, including reactive oxygen species (ROS), metabolites, nervous system, exerkines and lipolysis can facilitate exercise-mediated browning of WAT. In this review, the roles and the underlying mechanisms of exercise-mediated browning of WAT are summarized. The effects of different styles of exercise on the browning of WAT are also discussed, with the aim to propose better exercise strategies to enhance exercise-mediated browning of WAT, so as to promote metabolic health. Finally, the different reactivity of WAT at different anatomical sites to exercise-mediated browning is reviewed, which may provide potential suggestion for people with different fat loss needs.
format	article
author	Wang-Jing Mu Jie-Ying Zhu Min Chen Liang Guo
author_facet	Wang-Jing Mu Jie-Ying Zhu Min Chen Liang Guo
author_sort	Wang-Jing Mu
title	Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
title_short	Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
title_full	Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
title_fullStr	Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
title_full_unstemmed	Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
title_sort	exercise-mediated browning of white adipose tissue: its significance, mechanism and effectiveness
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c3eb8ac38636443aa406e224e115bf1c
work_keys_str_mv	AT wangjingmu exercisemediatedbrowningofwhiteadiposetissueitssignificancemechanismandeffectiveness AT jieyingzhu exercisemediatedbrowningofwhiteadiposetissueitssignificancemechanismandeffectiveness AT minchen exercisemediatedbrowningofwhiteadiposetissueitssignificancemechanismandeffectiveness AT liangguo exercisemediatedbrowningofwhiteadiposetissueitssignificancemechanismandeffectiveness
_version_	1718432202201497600

Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness

Ejemplares similares