Overexpression or Deletion of Ergosterol Biosynthesis Genes Alters Doubling Time, Response to Stress Agents, and Drug Susceptibility in <italic toggle="yes">Saccharomyces cerevisiae</italic>

ABSTRACT Ergosterol (ERG) is a critical sterol in the cell membranes of fungi, and its biosynthesis is tightly regulated by 25 known enzymes along the ERG production pathway. The effects of changes in expression of each ERG biosynthesis enzyme in Saccharomyces cerevisiae were analyzed by the use of...

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Bibliographic Details
Main Authors: Somanon Bhattacharya, Brooke D. Esquivel, Theodore C. White
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Online Access:https://doaj.org/article/c3f1bbde2b7e4472b74e0932c31f0805
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