Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer

Abstract Checkpoint inhibitors have demonstrated clinical impact in colorectal cancer with deficient mismatch repair and high microsatellite instability. However, the majority of patients have disease with stable microsatellites that responds poorly to immunotherapies. Combinations of checkpoint inh...

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Autores principales: Ryan J. Slovak, Hong-Jai Park, William M. Kamp, Johannes M. Ludwig, Insoo Kang, Hyun S. Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c3f1eaec71aa4d68a08a5f210792e245
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