Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa

This work presents a feasible process for preparation screen-printed electrode (SPE) using a lab-made conductive ink based on cellulose acetate (CAc) and graphite powder (GP) printed on polyvinyl chloride (PVC) sheet. The CAc present in the composition of this SPE is a binding agent for conductive i...

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Autores principales:	Jefferson H.S. Carvalho, Jeferson L. Gogola, Márcio F. Bergamini, Luiz H. Marcolino-Junior, Bruno C. Janegitz
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Disposable electrochemical sensors Conductive ink Cellulose acetate Levodopa Instruments and machines QA71-90
Acceso en línea:	https://doaj.org/article/c3f3363eef814c89ac60ee2d66855165
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spelling	oai:doaj.org-article:c3f3363eef814c89ac60ee2d668551652021-11-04T04:39:38ZDisposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa2666-053910.1016/j.snr.2021.100056https://doaj.org/article/c3f3363eef814c89ac60ee2d668551652021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S266605392100031Xhttps://doaj.org/toc/2666-0539This work presents a feasible process for preparation screen-printed electrode (SPE) using a lab-made conductive ink based on cellulose acetate (CAc) and graphite powder (GP) printed on polyvinyl chloride (PVC) sheet. The CAc present in the composition of this SPE is a binding agent for conductive inks with GP, which are relatively low-cost and easily obtainable materials, compared to other similar commercial sensors. The SPE was evaluated through cyclic voltammetry (CV) using an equimolar [Fe(CN)6]3-/4− solution as a redox probe to find an adequate ink composition. Electrode surface was characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). To show the analytical potential of SPE proposed it was used for Levodopa (L-dopa) determination. L-dopa is a drug frequently used to reduce the symptoms of Parkinson's disease. The GP-CAc/PVC electrode was evaluated for the determination of L-dopa under square wave voltammetric (SWV) conditions. The electrode presented a linear dynamic range (LDR) from 8.00 to 100 µmol L−1 and a limit of detection (LOD) of 0.06 µmol L−1. As a proof-of-concept, the proposed electrode was used to quantify L-dopa in drug samples as an alternative tool for quality control tests, being applied to two commercial drugs. The electrode construction strategy proved to be reproducible with an analytical performance comparable to other similar electrodes reported in the literature.Jefferson H.S. CarvalhoJeferson L. GogolaMárcio F. BergaminiLuiz H. Marcolino-JuniorBruno C. JanegitzElsevierarticleDisposable electrochemical sensorsConductive inkCellulose acetateLevodopaInstruments and machinesQA71-90ENSensors and Actuators Reports, Vol 3, Iss , Pp 100056- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Disposable electrochemical sensors Conductive ink Cellulose acetate Levodopa Instruments and machines QA71-90
spellingShingle	Disposable electrochemical sensors Conductive ink Cellulose acetate Levodopa Instruments and machines QA71-90 Jefferson H.S. Carvalho Jeferson L. Gogola Márcio F. Bergamini Luiz H. Marcolino-Junior Bruno C. Janegitz Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa
description	This work presents a feasible process for preparation screen-printed electrode (SPE) using a lab-made conductive ink based on cellulose acetate (CAc) and graphite powder (GP) printed on polyvinyl chloride (PVC) sheet. The CAc present in the composition of this SPE is a binding agent for conductive inks with GP, which are relatively low-cost and easily obtainable materials, compared to other similar commercial sensors. The SPE was evaluated through cyclic voltammetry (CV) using an equimolar [Fe(CN)6]3-/4− solution as a redox probe to find an adequate ink composition. Electrode surface was characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). To show the analytical potential of SPE proposed it was used for Levodopa (L-dopa) determination. L-dopa is a drug frequently used to reduce the symptoms of Parkinson's disease. The GP-CAc/PVC electrode was evaluated for the determination of L-dopa under square wave voltammetric (SWV) conditions. The electrode presented a linear dynamic range (LDR) from 8.00 to 100 µmol L−1 and a limit of detection (LOD) of 0.06 µmol L−1. As a proof-of-concept, the proposed electrode was used to quantify L-dopa in drug samples as an alternative tool for quality control tests, being applied to two commercial drugs. The electrode construction strategy proved to be reproducible with an analytical performance comparable to other similar electrodes reported in the literature.
format	article
author	Jefferson H.S. Carvalho Jeferson L. Gogola Márcio F. Bergamini Luiz H. Marcolino-Junior Bruno C. Janegitz
author_facet	Jefferson H.S. Carvalho Jeferson L. Gogola Márcio F. Bergamini Luiz H. Marcolino-Junior Bruno C. Janegitz
author_sort	Jefferson H.S. Carvalho
title	Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa
title_short	Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa
title_full	Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa
title_fullStr	Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa
title_full_unstemmed	Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa
title_sort	disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of l-dopa
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/c3f3363eef814c89ac60ee2d66855165
work_keys_str_mv	AT jeffersonhscarvalho disposableandlowcostlabmadescreenprintedelectrodesforvoltammetricdeterminationofldopa AT jefersonlgogola disposableandlowcostlabmadescreenprintedelectrodesforvoltammetricdeterminationofldopa AT marciofbergamini disposableandlowcostlabmadescreenprintedelectrodesforvoltammetricdeterminationofldopa AT luizhmarcolinojunior disposableandlowcostlabmadescreenprintedelectrodesforvoltammetricdeterminationofldopa AT brunocjanegitz disposableandlowcostlabmadescreenprintedelectrodesforvoltammetricdeterminationofldopa
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Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa

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