Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)

Background: Little is known about longitudinal prescribing practices for anti-epileptic drugs (AEDs) in South Africa. The prescribing patterns and associated direct medicine costs of AEDs in the private health sector were investigated, using claims data from January 1, 2008 to December 31, 2013. Me...

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Autores principales:	Karen Jacobs, Marlene Julyan, Martie S. Lubbe, Johanita R. Burger, Marike Cockeran
Formato:	article
Lenguaje:	EN
Publicado:	AOSIS 2016
Materias:	anti-epileptic direct medicine costs longitudinal medicine claims database prescribing patterns south africa Medicine R
Acceso en línea:	https://doaj.org/article/c3fef04a408b42488a06c472c89a69a1
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spelling	oai:doaj.org-article:c3fef04a408b42488a06c472c89a69a12021-11-24T07:44:18ZAnti-epileptic prescribing patterns in the South African private health sector (2008–2013)2078-61902078-620410.4102/safp.v58i4.5443https://doaj.org/article/c3fef04a408b42488a06c472c89a69a12016-08-01T00:00:00Zhttps://safpj.co.za/index.php/safpj/article/view/5443https://doaj.org/toc/2078-6190https://doaj.org/toc/2078-6204Background: Little is known about longitudinal prescribing practices for anti-epileptic drugs (AEDs) in South Africa. The prescribing patterns and associated direct medicine costs of AEDs in the private health sector were investigated, using claims data from January 1, 2008 to December 31, 2013. Methods: The annual prevalence of prescriptions, AEDs and AED generics per patient with epilepsy (ICD-10 code G40) was determined. Cost analyses conducted included the calculation of the total direct cost of AEDs (medical scheme contribution, patient co-payment, and single exit price (SEP)), and the average cost per AED per year. Results: Prevalence of patients claiming anti-epileptics ranged between 0.87% and 0.91% from 2008 to 2013. AED prescriptions/patient ranged from 11.76 (95% CI, 11.56–11.95)] in 2008 to 11.90 (95% CI, 11.71–12.09) in 2013. Patients aged 40–65 years had the highest number of AED prescriptions/year. Valproate was most prescribed, followed by lamotrigine and carbamazepine. Average cost per AED increased from R237.12 (95% CI, 233.58–240.65) in 2008 to R522.32 (95% CI, 515.24–529.41) in 2013, while the average patient co-payments increased from R27.76 (95% CI, 26.63–28.89) to R264.32 (95% CI, 260.61–268.03). Prescribing of generics increased by 12.84%. Conclusions: Generic prescribing increased over time; however, patient co-payments increased dramatically.Karen JacobsMarlene JulyanMartie S. LubbeJohanita R. BurgerMarike CockeranAOSISarticleanti-epilepticdirect medicine costslongitudinalmedicine claims databaseprescribing patternssouth africaMedicineRENSouth African Family Practice, Vol 58, Iss 4 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	anti-epileptic direct medicine costs longitudinal medicine claims database prescribing patterns south africa Medicine R
spellingShingle	anti-epileptic direct medicine costs longitudinal medicine claims database prescribing patterns south africa Medicine R Karen Jacobs Marlene Julyan Martie S. Lubbe Johanita R. Burger Marike Cockeran Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)
description	Background: Little is known about longitudinal prescribing practices for anti-epileptic drugs (AEDs) in South Africa. The prescribing patterns and associated direct medicine costs of AEDs in the private health sector were investigated, using claims data from January 1, 2008 to December 31, 2013. Methods: The annual prevalence of prescriptions, AEDs and AED generics per patient with epilepsy (ICD-10 code G40) was determined. Cost analyses conducted included the calculation of the total direct cost of AEDs (medical scheme contribution, patient co-payment, and single exit price (SEP)), and the average cost per AED per year. Results: Prevalence of patients claiming anti-epileptics ranged between 0.87% and 0.91% from 2008 to 2013. AED prescriptions/patient ranged from 11.76 (95% CI, 11.56–11.95)] in 2008 to 11.90 (95% CI, 11.71–12.09) in 2013. Patients aged 40–65 years had the highest number of AED prescriptions/year. Valproate was most prescribed, followed by lamotrigine and carbamazepine. Average cost per AED increased from R237.12 (95% CI, 233.58–240.65) in 2008 to R522.32 (95% CI, 515.24–529.41) in 2013, while the average patient co-payments increased from R27.76 (95% CI, 26.63–28.89) to R264.32 (95% CI, 260.61–268.03). Prescribing of generics increased by 12.84%. Conclusions: Generic prescribing increased over time; however, patient co-payments increased dramatically.
format	article
author	Karen Jacobs Marlene Julyan Martie S. Lubbe Johanita R. Burger Marike Cockeran
author_facet	Karen Jacobs Marlene Julyan Martie S. Lubbe Johanita R. Burger Marike Cockeran
author_sort	Karen Jacobs
title	Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)
title_short	Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)
title_full	Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)
title_fullStr	Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)
title_full_unstemmed	Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)
title_sort	anti-epileptic prescribing patterns in the south african private health sector (2008–2013)
publisher	AOSIS
publishDate	2016
url	https://doaj.org/article/c3fef04a408b42488a06c472c89a69a1
work_keys_str_mv	AT karenjacobs antiepilepticprescribingpatternsinthesouthafricanprivatehealthsector20082013 AT marlenejulyan antiepilepticprescribingpatternsinthesouthafricanprivatehealthsector20082013 AT martieslubbe antiepilepticprescribingpatternsinthesouthafricanprivatehealthsector20082013 AT johanitarburger antiepilepticprescribingpatternsinthesouthafricanprivatehealthsector20082013 AT marikecockeran antiepilepticprescribingpatternsinthesouthafricanprivatehealthsector20082013
_version_	1718415883600134144

Anti-epileptic prescribing patterns in the South African private health sector (2008–2013)

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