Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

<h4>Background</h4>Highly charged compounds typically suffer from low membrane permeability and thus are generally regarded as sub-optimal drug candidates. Nonetheless, the highly charged drug fosmidomycin and its more active methyl-derivative FR900098 have proven parasiticidal activity...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Stefan Baumeister, Jochen Wiesner, Armin Reichenberg, Martin Hintz, Sven Bietz, Omar S Harb, David S Roos, Maximilian Kordes, Johannes Friesen, Kai Matuschewski, Klaus Lingelbach, Hassan Jomaa, Frank Seeber
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/c4027a7c21c4431683f79eb680d83406
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares