Development of a physical model-based algorithm for the detection of single-nucleotide substitutions by using tiling microarrays.

High-density DNA microarrays are useful tools for analyzing sequence changes in DNA samples. Although microarray analysis provides informative signals from a large number of probes, the analysis and interpretation of these signals have certain inherent limitations, namely, complex dependency of sign...

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Bibliographic Details
Main Authors: Naoaki Ono, Shingo Suzuki, Chikara Furusawa, Hiroshi Shimizu, Tetsuya Yomo
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/c4056a9e5ed84dd088b4bd288eeb8da1
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