Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation

Theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another in the absence of proteins. Here, the authors show that GC-rich DNA with methylated cytosine and AT-rich DNA duplexes associate more strongly than GC-rich duplexes regardless of the sequence homolo...

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Autores principales:	Jejoong Yoo, Hajin Kim, Aleksei Aksimentiev, Taekjip Ha
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c40d2f4f315e48da9b0b3d60a2ebb5fa
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spelling	oai:doaj.org-article:c40d2f4f315e48da9b0b3d60a2ebb5fa2021-12-02T17:32:50ZDirect evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation10.1038/ncomms110452041-1723https://doaj.org/article/c40d2f4f315e48da9b0b3d60a2ebb5fa2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11045https://doaj.org/toc/2041-1723Theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another in the absence of proteins. Here, the authors show that GC-rich DNA with methylated cytosine and AT-rich DNA duplexes associate more strongly than GC-rich duplexes regardless of the sequence homology.Jejoong YooHajin KimAleksei AksimentievTaekjip HaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jejoong Yoo Hajin Kim Aleksei Aksimentiev Taekjip Ha Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
description	Theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another in the absence of proteins. Here, the authors show that GC-rich DNA with methylated cytosine and AT-rich DNA duplexes associate more strongly than GC-rich duplexes regardless of the sequence homology.
format	article
author	Jejoong Yoo Hajin Kim Aleksei Aksimentiev Taekjip Ha
author_facet	Jejoong Yoo Hajin Kim Aleksei Aksimentiev Taekjip Ha
author_sort	Jejoong Yoo
title	Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
title_short	Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
title_full	Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
title_fullStr	Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
title_full_unstemmed	Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
title_sort	direct evidence for sequence-dependent attraction between double-stranded dna controlled by methylation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c40d2f4f315e48da9b0b3d60a2ebb5fa
work_keys_str_mv	AT jejoongyoo directevidenceforsequencedependentattractionbetweendoublestrandeddnacontrolledbymethylation AT hajinkim directevidenceforsequencedependentattractionbetweendoublestrandeddnacontrolledbymethylation AT alekseiaksimentiev directevidenceforsequencedependentattractionbetweendoublestrandeddnacontrolledbymethylation AT taekjipha directevidenceforsequencedependentattractionbetweendoublestrandeddnacontrolledbymethylation
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Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation

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