Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation

Theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another in the absence of proteins. Here, the authors show that GC-rich DNA with methylated cytosine and AT-rich DNA duplexes associate more strongly than GC-rich duplexes regardless of the sequence homolo...

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Auteurs principaux: Jejoong Yoo, Hajin Kim, Aleksei Aksimentiev, Taekjip Ha
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/c40d2f4f315e48da9b0b3d60a2ebb5fa
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