Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports

The current unhealthy diets and sedentary lifestyle have led to increase in the prevalence of diabetes and metabolic syndrome globally. Fatty liver is a common occurrence in metabolic syndrome. The liver health is often ignored due to delayed warning signs. Fatty changes of the liver is one of the c...

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Autores principales:	Amit Kharat, Nikhith Soman Vanpully, Jacob Cheeran Jeeson
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Materias:	elastography magnetic resonance elastography liver stiffness elastograms Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/c427097b8acb4e2c9b369747bfa2afa3
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spelling	oai:doaj.org-article:c427097b8acb4e2c9b369747bfa2afa32021-11-13T23:32:30ZSimplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports0971-30261998-380810.1055/s-0041-1735929https://doaj.org/article/c427097b8acb4e2c9b369747bfa2afa32021-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1735929https://doaj.org/toc/0971-3026https://doaj.org/toc/1998-3808The current unhealthy diets and sedentary lifestyle have led to increase in the prevalence of diabetes and metabolic syndrome globally. Fatty liver is a common occurrence in metabolic syndrome. The liver health is often ignored due to delayed warning signs. Fatty changes of the liver is one of the common findings in ultrasonography. Ultrasound does not detect fibrosis except when cirrhosis is developed. Early stages of fibrosis are asymptomatic with no significant laboratory or preliminary imaging findings. With fibrosis, the elasticity of the liver is reduced and becomes stiffer. Over the years, many techniques have developed to assess the stiffness of the liver, starting from palpation, ultrasonography, and recently developed magnetic resonance elastography (MRE). In this article, we have tried to simplify the concepts of MRE to detect fibrosis and present few case reports. The basic steps involved in generating elastograms and interpretation with some insight on how to incorporate it into the clinical workflow are discussed. MRE is superior to various other available techniques and even offers certain advantages over biopsy. MRE is FDA approved for liver fibrosis since 2009, yet it is hardly used in the Indian setting. MRE is a safe and noninvasive technique to evaluate a large volume of the liver and can be a new norm for the evaluation of fatty liver. Magnetic resonance imaging (MRI)-based elastography techniques hold an exciting future in providing mechanical properties of tissues in various organs like spleen, brain, kidney, and heart.Amit KharatNikhith Soman VanpullyJacob Cheeran JeesonThieme Medical and Scientific Publishers Pvt. Ltd.articleelastographymagnetic resonance elastographyliver stiffnesselastogramsMedical physics. Medical radiology. Nuclear medicineR895-920ENIndian Journal of Radiology and Imaging, Vol 31, Iss 03, Pp 644-652 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	elastography magnetic resonance elastography liver stiffness elastograms Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	elastography magnetic resonance elastography liver stiffness elastograms Medical physics. Medical radiology. Nuclear medicine R895-920 Amit Kharat Nikhith Soman Vanpully Jacob Cheeran Jeeson Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
description	The current unhealthy diets and sedentary lifestyle have led to increase in the prevalence of diabetes and metabolic syndrome globally. Fatty liver is a common occurrence in metabolic syndrome. The liver health is often ignored due to delayed warning signs. Fatty changes of the liver is one of the common findings in ultrasonography. Ultrasound does not detect fibrosis except when cirrhosis is developed. Early stages of fibrosis are asymptomatic with no significant laboratory or preliminary imaging findings. With fibrosis, the elasticity of the liver is reduced and becomes stiffer. Over the years, many techniques have developed to assess the stiffness of the liver, starting from palpation, ultrasonography, and recently developed magnetic resonance elastography (MRE). In this article, we have tried to simplify the concepts of MRE to detect fibrosis and present few case reports. The basic steps involved in generating elastograms and interpretation with some insight on how to incorporate it into the clinical workflow are discussed. MRE is superior to various other available techniques and even offers certain advantages over biopsy. MRE is FDA approved for liver fibrosis since 2009, yet it is hardly used in the Indian setting. MRE is a safe and noninvasive technique to evaluate a large volume of the liver and can be a new norm for the evaluation of fatty liver. Magnetic resonance imaging (MRI)-based elastography techniques hold an exciting future in providing mechanical properties of tissues in various organs like spleen, brain, kidney, and heart.
format	article
author	Amit Kharat Nikhith Soman Vanpully Jacob Cheeran Jeeson
author_facet	Amit Kharat Nikhith Soman Vanpully Jacob Cheeran Jeeson
author_sort	Amit Kharat
title	Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
title_short	Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
title_full	Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
title_fullStr	Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
title_full_unstemmed	Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
title_sort	simplified guide to mr elastography in early detection of hepatic fibrosis with case reports
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2021
url	https://doaj.org/article/c427097b8acb4e2c9b369747bfa2afa3
work_keys_str_mv	AT amitkharat simplifiedguidetomrelastographyinearlydetectionofhepaticfibrosiswithcasereports AT nikhithsomanvanpully simplifiedguidetomrelastographyinearlydetectionofhepaticfibrosiswithcasereports AT jacobcheeranjeeson simplifiedguidetomrelastographyinearlydetectionofhepaticfibrosiswithcasereports
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Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports

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