Microbiota-Derived Short-Chain Fatty Acids Promote LAMTOR2-Mediated Immune Responses in Macrophages

Microbiota-Derived Short-Chain Fatty Acids Promote LAMTOR2-Mediated Immune Responses in Macrophages

ABSRTACT Klebsiella pneumoniae is a common cause of human-pneumonia-derived sepsis with high morbidity and mortality. The microbiota promotes and maintains host immune homeostasis. The mechanisms by which the gut microbiota affects the host defenses in the respiratory system systematically, however,...

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Bibliographic Details
Main Authors: Ting Wu, Hongru Li, Cong Su, Fangming Xu, Guangwei Yang, Kaili Sun, Mengran Xu, Na Lv, Bao Meng, Yanyan Liu, Lifen Hu, Yan Liu, Yufeng Gao, Heng Wang, Yanhu Lan, Dexiang Xu, Jiabin Li
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
K. pneumoniae
gut microbiota
immune responses
SCFAs
LAMTOR2
mechanisms
Microbiology
QR1-502
Online Access:https://doaj.org/article/c4284f90add142ebb3e54f0359dc9604
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https://doaj.org/article/c4284f90add142ebb3e54f0359dc9604

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