MeCP2 regulates gene expression through recognition of H3K27me3

MeCP2 is a transcriptional repressor and associates with nucleosomes. Here the authors show interaction of MeCP2 and H3K27me3 by biochemical assay and chromatin immunoprecipitation sequencing analysis.

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Detalles Bibliográficos
Autores principales: Wooje Lee, Jeeho Kim, Jung-Mi Yun, Takbum Ohn, Qizhi Gong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c42dda5d375043e397a8b5d749239afe
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Sumario:MeCP2 is a transcriptional repressor and associates with nucleosomes. Here the authors show interaction of MeCP2 and H3K27me3 by biochemical assay and chromatin immunoprecipitation sequencing analysis.