Belimumab for Immune-Mediated Necrotizing Myopathy Associated With Anti-SRP Antibodies: A Case Report and Retrospective Review of Patients Treated With Anti-B-Cell Therapy in a Single Center and Literature

Belimumab for Immune-Mediated Necrotizing Myopathy Associated With Anti-SRP Antibodies: A Case Report and Retrospective Review of Patients Treated With Anti-B-Cell Therapy in a Single Center and Literature

BackgroundImmune-mediated necrotizing myopathy (IMNM) is characterized by markedly elevated creatinine kinase and histologically scattered necrotic muscle fibers and generally associated with autoantibodies against signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl-coA-reductase (HMGCR)...

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Autores principales: Bei-Bei Cui, Yun-Ru Tian, Xin-Yue Ma, Geng Yin, Qibing Xie
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
immune-mediated necrotizing myopathy
SRP antibody
refractory IMNM
belimumab
BAFF
rituximab
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/c4341f43298f4987bc701627bdd9263e
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