Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction

Adenocarcinoma at the gastroesophageal junction has a dismal prognosis and few drug options. Here, the authors present genomic and transcriptomic features and potential therapeutic targets and prognostic biomarkers of Chinese and Caucasian tumours, and reveal the molecular similarities.

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Detalles Bibliográficos
Autores principales: Yuan Lin, Yingying Luo, Yanxia Sun, Wenjia Guo, Xuan Zhao, Yiyi Xi, Yuling Ma, Mingming Shao, Wen Tan, Ge Gao, Chen Wu, Dongxin Lin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c436c63633644f689042acf518860914
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Sumario:Adenocarcinoma at the gastroesophageal junction has a dismal prognosis and few drug options. Here, the authors present genomic and transcriptomic features and potential therapeutic targets and prognostic biomarkers of Chinese and Caucasian tumours, and reveal the molecular similarities.