Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction

Adenocarcinoma at the gastroesophageal junction has a dismal prognosis and few drug options. Here, the authors present genomic and transcriptomic features and potential therapeutic targets and prognostic biomarkers of Chinese and Caucasian tumours, and reveal the molecular similarities.

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Autores principales:	Yuan Lin, Yingying Luo, Yanxia Sun, Wenjia Guo, Xuan Zhao, Yiyi Xi, Yuling Ma, Mingming Shao, Wen Tan, Ge Gao, Chen Wu, Dongxin Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c436c63633644f689042acf518860914
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spelling	oai:doaj.org-article:c436c63633644f689042acf5188609142021-12-02T14:41:23ZGenomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction10.1038/s41467-020-19949-62041-1723https://doaj.org/article/c436c63633644f689042acf5188609142020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19949-6https://doaj.org/toc/2041-1723Adenocarcinoma at the gastroesophageal junction has a dismal prognosis and few drug options. Here, the authors present genomic and transcriptomic features and potential therapeutic targets and prognostic biomarkers of Chinese and Caucasian tumours, and reveal the molecular similarities.Yuan LinYingying LuoYanxia SunWenjia GuoXuan ZhaoYiyi XiYuling MaMingming ShaoWen TanGe GaoChen WuDongxin LinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuan Lin Yingying Luo Yanxia Sun Wenjia Guo Xuan Zhao Yiyi Xi Yuling Ma Mingming Shao Wen Tan Ge Gao Chen Wu Dongxin Lin Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
description	Adenocarcinoma at the gastroesophageal junction has a dismal prognosis and few drug options. Here, the authors present genomic and transcriptomic features and potential therapeutic targets and prognostic biomarkers of Chinese and Caucasian tumours, and reveal the molecular similarities.
format	article
author	Yuan Lin Yingying Luo Yanxia Sun Wenjia Guo Xuan Zhao Yiyi Xi Yuling Ma Mingming Shao Wen Tan Ge Gao Chen Wu Dongxin Lin
author_facet	Yuan Lin Yingying Luo Yanxia Sun Wenjia Guo Xuan Zhao Yiyi Xi Yuling Ma Mingming Shao Wen Tan Ge Gao Chen Wu Dongxin Lin
author_sort	Yuan Lin
title	Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
title_short	Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
title_full	Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
title_fullStr	Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
title_full_unstemmed	Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
title_sort	genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c436c63633644f689042acf518860914
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Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction

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