An Antivirulence Approach for Preventing <named-content content-type="genus-species">Cryptococcus neoformans</named-content> from Crossing the Blood-Brain Barrier via Novel Natural Product Inhibitors of a Fungal Metalloprotease
ABSTRACT Cryptococcus neoformans (Cn) is the leading cause of fungal meningitis, a deadly disease with limited therapeutic options. Dissemination to the central nervous system hinges on the ability of Cn to breach the blood-brain barrier (BBB) and is considered an attribute of Cn virulence. Targetin...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2020
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| Accès en ligne: | https://doaj.org/article/c43badeac6a347d4a35d7a0eaae58e77 |
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