Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineages

Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineages

Summary: A quarter of all seasonal influenza cases are caused by type B influenza virus (IBV) that also dominates periodically. Here, we investigated a recombinant adenovirus vaccine carrying a synthetic HA2 representing the consensus sequence of all IBV hemagglutinins. The vaccine fully protected m...

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Détails bibliographiques
Auteurs principaux: Caroline Gravel, Abenaya Muralidharan, Amparo Duran, Adrian Zetner, Annabelle Pfeifle, Wanyue Zhang, Anwar Hashem, Levi Tamming, Aaron Farnsworth, Hugues Loemba, Wangxue Chen, Florian Krammer, David Safronetz, Jingxin Cao, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Gary Van Domselaar, Xuguang Li
Format: article
Langue:EN
Publié: Elsevier 2021
Sujets:
Immunology
immune response
Virology
Science
Q
Accès en ligne:https://doaj.org/article/c44338db000c4fca9f7baa27557288ba
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https://doaj.org/article/c44338db000c4fca9f7baa27557288ba

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