Prediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms.

Recent analyses of human genome sequences have given rise to impressive advances in identifying non-synonymous single nucleotide polymorphisms (nsSNPs). By contrast, the annotation of nsSNPs and their links to diseases are progressing at a much slower pace. Many of the current approaches to analysin...

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Bibliographic Details
Main Authors: Tammy M K Cheng, Yu-En Lu, Michele Vendruscolo, Pietro Lio', Tom L Blundell
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
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Online Access:https://doaj.org/article/c4457e324d0a456987d7b6e7200d27f1
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