Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’

Abstract Mitochondrial function can provide key insights into how fish will respond to climate change, due to its important role in heart performance, energy metabolism and oxidative stress. However, whether warm acclimation can maintain or improve the energetic status of the fish heart when exposed...

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Autores principales:	Lucie Gerber, Kathy A. Clow, Felix C. Mark, Anthony K. Gamperl
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c446bac6c66e44928dd08135080c3436
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spelling	oai:doaj.org-article:c446bac6c66e44928dd08135080c34362021-12-02T16:18:06ZImproved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’10.1038/s41598-020-78519-42045-2322https://doaj.org/article/c446bac6c66e44928dd08135080c34362020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78519-4https://doaj.org/toc/2045-2322Abstract Mitochondrial function can provide key insights into how fish will respond to climate change, due to its important role in heart performance, energy metabolism and oxidative stress. However, whether warm acclimation can maintain or improve the energetic status of the fish heart when exposed to short-term heat stress is not well understood. We acclimated Atlantic salmon, a highly aerobic eurythermal species, to 12 and 20 °C, then measured cardiac mitochondrial functionality and integrity at 20 °C and at 24, 26 and 28 °C (this species’ critical thermal maximum ± 2 °C). Acclimation to 20 °C vs. 12 °C enhanced many aspects of mitochondrial respiratory capacity and efficiency up to 24 °C, and preserved outer mitochondrial membrane integrity up to 26 °C. Further, reactive oxygen species (ROS) production was dramatically decreased at all temperatures. These data suggest that salmon acclimated to ‘normal’ maximum summer temperatures are capable of surviving all but the most extreme ocean heat waves, and that there is no ‘tradeoff’ in heart mitochondrial function when Atlantic salmon are acclimated to high temperatures (i.e., increased oxidative phosphorylation does not result in heightened ROS production). This study suggests that fish species may show quite different acclimatory responses when exposed to prolonged high temperatures, and thus, susceptibility to climate warming.Lucie GerberKathy A. ClowFelix C. MarkAnthony K. GamperlNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lucie Gerber Kathy A. Clow Felix C. Mark Anthony K. Gamperl Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
description	Abstract Mitochondrial function can provide key insights into how fish will respond to climate change, due to its important role in heart performance, energy metabolism and oxidative stress. However, whether warm acclimation can maintain or improve the energetic status of the fish heart when exposed to short-term heat stress is not well understood. We acclimated Atlantic salmon, a highly aerobic eurythermal species, to 12 and 20 °C, then measured cardiac mitochondrial functionality and integrity at 20 °C and at 24, 26 and 28 °C (this species’ critical thermal maximum ± 2 °C). Acclimation to 20 °C vs. 12 °C enhanced many aspects of mitochondrial respiratory capacity and efficiency up to 24 °C, and preserved outer mitochondrial membrane integrity up to 26 °C. Further, reactive oxygen species (ROS) production was dramatically decreased at all temperatures. These data suggest that salmon acclimated to ‘normal’ maximum summer temperatures are capable of surviving all but the most extreme ocean heat waves, and that there is no ‘tradeoff’ in heart mitochondrial function when Atlantic salmon are acclimated to high temperatures (i.e., increased oxidative phosphorylation does not result in heightened ROS production). This study suggests that fish species may show quite different acclimatory responses when exposed to prolonged high temperatures, and thus, susceptibility to climate warming.
format	article
author	Lucie Gerber Kathy A. Clow Felix C. Mark Anthony K. Gamperl
author_facet	Lucie Gerber Kathy A. Clow Felix C. Mark Anthony K. Gamperl
author_sort	Lucie Gerber
title	Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
title_short	Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
title_full	Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
title_fullStr	Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
title_full_unstemmed	Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
title_sort	improved mitochondrial function in salmon (salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c446bac6c66e44928dd08135080c3436
work_keys_str_mv	AT luciegerber improvedmitochondrialfunctioninsalmonsalmosalarfollowinghightemperatureacclimationsuggeststhattherearecracksintheproverbialceiling AT kathyaclow improvedmitochondrialfunctioninsalmonsalmosalarfollowinghightemperatureacclimationsuggeststhattherearecracksintheproverbialceiling AT felixcmark improvedmitochondrialfunctioninsalmonsalmosalarfollowinghightemperatureacclimationsuggeststhattherearecracksintheproverbialceiling AT anthonykgamperl improvedmitochondrialfunctioninsalmonsalmosalarfollowinghightemperatureacclimationsuggeststhattherearecracksintheproverbialceiling
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Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’

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