Continuous performance task in ADHD: Is reaction time variability a key measure?

Florence Levy,1 Andrew Pipingas,2 Elizabeth V Harris,2 Maree Farrow,3 Richard B Silberstein2 1School of Psychiatry, University of New South Wales and Head, Child and Family East, Prince of Wales Hospital, Sydney, NSW, Australia; 2Centre for Human Psychopharmacology, Swinburne University of Technolo...

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Autores principales:	Levy F, Pipingas A, Harris EV, Farrow M, Silberstein RB
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	ADHD Continuous Performance Task Reaction Time Variability Stimulant medication Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/c4470e8efc0c403fba4f8ef75aa7867e
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id	oai:doaj.org-article:c4470e8efc0c403fba4f8ef75aa7867e
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spelling	oai:doaj.org-article:c4470e8efc0c403fba4f8ef75aa7867e2021-12-02T02:03:35ZContinuous performance task in ADHD: Is reaction time variability a key measure?1178-2021https://doaj.org/article/c4470e8efc0c403fba4f8ef75aa7867e2018-03-01T00:00:00Zhttps://www.dovepress.com/continuous-performance-task-in-adhd-is-reaction-time-variability-a-key-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Florence Levy,1 Andrew Pipingas,2 Elizabeth V Harris,2 Maree Farrow,3 Richard B Silberstein2 1School of Psychiatry, University of New South Wales and Head, Child and Family East, Prince of Wales Hospital, Sydney, NSW, Australia; 2Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Victoria, Australia; 3Wicking Dementia Research and Education Centre, University of Tasmania, Hobart, Tasmania, Australia Objective: To compare the use of the Continuous Performance Task (CPT) reaction time variability (intraindividual variability or standard deviation of reaction time), as a measure of vigilance in attention-deficit hyperactivity disorder (ADHD), and stimulant medication response, utilizing a simple CPT X-task vs an A-X-task. Method: Comparative analyses of two separate X-task vs A-X-task data sets, and subgroup analyses of performance on and off medication were conducted. Results: The CPT X-task reaction time variability had a direct relationship to ADHD clinician severity ratings, unlike the CPT A-X-task. Variability in X-task performance was reduced by medication compared with the children’s unmedicated performance, but this effect did not reach significance. When the coefficient of variation was applied, severity measures and medication response were significant for the X-task, but not for the A-X-task. Conclusion: The CPT-X-task is a useful clinical screening test for ADHD and medication response. In particular, reaction time variability is related to default mode interference. The A-X-task is less useful in this regard. Keywords: ADHD, continuous performance task, reaction time variability, stimulant medicationLevy FPipingas AHarris EVFarrow MSilberstein RBDove Medical PressarticleADHDContinuous Performance TaskReaction Time VariabilityStimulant medicationNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 781-786 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	ADHD Continuous Performance Task Reaction Time Variability Stimulant medication Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	ADHD Continuous Performance Task Reaction Time Variability Stimulant medication Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Levy F Pipingas A Harris EV Farrow M Silberstein RB Continuous performance task in ADHD: Is reaction time variability a key measure?
description	Florence Levy,1 Andrew Pipingas,2 Elizabeth V Harris,2 Maree Farrow,3 Richard B Silberstein2 1School of Psychiatry, University of New South Wales and Head, Child and Family East, Prince of Wales Hospital, Sydney, NSW, Australia; 2Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Victoria, Australia; 3Wicking Dementia Research and Education Centre, University of Tasmania, Hobart, Tasmania, Australia Objective: To compare the use of the Continuous Performance Task (CPT) reaction time variability (intraindividual variability or standard deviation of reaction time), as a measure of vigilance in attention-deficit hyperactivity disorder (ADHD), and stimulant medication response, utilizing a simple CPT X-task vs an A-X-task. Method: Comparative analyses of two separate X-task vs A-X-task data sets, and subgroup analyses of performance on and off medication were conducted. Results: The CPT X-task reaction time variability had a direct relationship to ADHD clinician severity ratings, unlike the CPT A-X-task. Variability in X-task performance was reduced by medication compared with the children’s unmedicated performance, but this effect did not reach significance. When the coefficient of variation was applied, severity measures and medication response were significant for the X-task, but not for the A-X-task. Conclusion: The CPT-X-task is a useful clinical screening test for ADHD and medication response. In particular, reaction time variability is related to default mode interference. The A-X-task is less useful in this regard. Keywords: ADHD, continuous performance task, reaction time variability, stimulant medication
format	article
author	Levy F Pipingas A Harris EV Farrow M Silberstein RB
author_facet	Levy F Pipingas A Harris EV Farrow M Silberstein RB
author_sort	Levy F
title	Continuous performance task in ADHD: Is reaction time variability a key measure?
title_short	Continuous performance task in ADHD: Is reaction time variability a key measure?
title_full	Continuous performance task in ADHD: Is reaction time variability a key measure?
title_fullStr	Continuous performance task in ADHD: Is reaction time variability a key measure?
title_full_unstemmed	Continuous performance task in ADHD: Is reaction time variability a key measure?
title_sort	continuous performance task in adhd: is reaction time variability a key measure?
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/c4470e8efc0c403fba4f8ef75aa7867e
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_version_	1718402733322534912

Continuous performance task in ADHD: Is reaction time variability a key measure?

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