Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones

Introduction: To assess the therapeutic efficacy of potassium citrate in the nonsurgical management of renal stones we run this research. The prophylactic effects of Potassium Citrate over renal stone formation have been established but there is still a gap for its therapeutic effect. Methods: A wr...

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Autores principales:	Fateme Guitynavard, Seyed Saeed Tamehri Zadeh, Mahin Ahmadi Pishkuhi, Sepideh Ebrahimi, Alireza Namazi Shabestari
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2021
Materias:	renal stones potassium citrate stone-free rate Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/c45b5519562f4a7bb7bedc4ce058bc3a
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spelling	oai:doaj.org-article:c45b5519562f4a7bb7bedc4ce058bc3a2021-11-30T08:31:41ZTherapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones10.22034/TRU.2021.295144.10742717-042Xhttps://doaj.org/article/c45b5519562f4a7bb7bedc4ce058bc3a2021-09-01T00:00:00Zhttps://www.transresurology.com/article_136487.htmlhttps://doaj.org/toc/2717-042XIntroduction: To assess the therapeutic efficacy of potassium citrate in the nonsurgical management of renal stones we run this research. The prophylactic effects of Potassium Citrate over renal stone formation have been established but there is still a gap for its therapeutic effect. Methods: A written informed consent was given to the patients who fulfilled the inclusion criteria and were interested in participation. Eventually 56 patients (Mean age= 43.7 ± 10.8) from June 2018 to December 2018 with a total of 86 renal stones enrolled in the study and treated with potassium citrate (10 mEq Alithoral, Nooria Darman Pasargad, tablets, three times a day). Moreover, the patients were recommended to reduce sodium intake as well as oxalate-rich foods, have at least 2 liters of water per day and normalize calcium intake. Finally, they were assessed 8 weeks after the treatment initiation, while in those whose stones were remained, the assessments repeated for another 8-week. Results: Based on our findings, 42 and 25 stones were completely dissolved at the first and second visit, respectively. Compared to the baseline parameters, the mean size of stones in the largest diameter decreased significantly from 5.13 to 1.96 mm and 5.13 to 0.79 mm (p-value<0.001) at the first and second visit, respectively. Conclusion: Potassium citrate plays a crucial role in pulverizing and also reduction of the dimensions of the renal stone. Therefore, apart from the prevention of renal stones recurrence, potassium citrate can be used in favor of treating renal stones.Fateme GuitynavardSeyed Saeed Tamehri ZadehMahin Ahmadi PishkuhiSepideh EbrahimiAlireza Namazi ShabestariUrology Research Centerarticlerenal stonespotassium citratestone-free rateDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 3, Iss 3, Pp 131-135 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	renal stones potassium citrate stone-free rate Diseases of the genitourinary system. Urology RC870-923
spellingShingle	renal stones potassium citrate stone-free rate Diseases of the genitourinary system. Urology RC870-923 Fateme Guitynavard Seyed Saeed Tamehri Zadeh Mahin Ahmadi Pishkuhi Sepideh Ebrahimi Alireza Namazi Shabestari Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones
description	Introduction: To assess the therapeutic efficacy of potassium citrate in the nonsurgical management of renal stones we run this research. The prophylactic effects of Potassium Citrate over renal stone formation have been established but there is still a gap for its therapeutic effect. Methods: A written informed consent was given to the patients who fulfilled the inclusion criteria and were interested in participation. Eventually 56 patients (Mean age= 43.7 ± 10.8) from June 2018 to December 2018 with a total of 86 renal stones enrolled in the study and treated with potassium citrate (10 mEq Alithoral, Nooria Darman Pasargad, tablets, three times a day). Moreover, the patients were recommended to reduce sodium intake as well as oxalate-rich foods, have at least 2 liters of water per day and normalize calcium intake. Finally, they were assessed 8 weeks after the treatment initiation, while in those whose stones were remained, the assessments repeated for another 8-week. Results: Based on our findings, 42 and 25 stones were completely dissolved at the first and second visit, respectively. Compared to the baseline parameters, the mean size of stones in the largest diameter decreased significantly from 5.13 to 1.96 mm and 5.13 to 0.79 mm (p-value<0.001) at the first and second visit, respectively. Conclusion: Potassium citrate plays a crucial role in pulverizing and also reduction of the dimensions of the renal stone. Therefore, apart from the prevention of renal stones recurrence, potassium citrate can be used in favor of treating renal stones.
format	article
author	Fateme Guitynavard Seyed Saeed Tamehri Zadeh Mahin Ahmadi Pishkuhi Sepideh Ebrahimi Alireza Namazi Shabestari
author_facet	Fateme Guitynavard Seyed Saeed Tamehri Zadeh Mahin Ahmadi Pishkuhi Sepideh Ebrahimi Alireza Namazi Shabestari
author_sort	Fateme Guitynavard
title	Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones
title_short	Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones
title_full	Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones
title_fullStr	Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones
title_full_unstemmed	Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones
title_sort	therapeutic efficacy of potassium citrate for treating less than 10-millimeter renal stones
publisher	Urology Research Center
publishDate	2021
url	https://doaj.org/article/c45b5519562f4a7bb7bedc4ce058bc3a
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Therapeutic Efficacy of Potassium Citrate for Treating Less Than 10-Millimeter Renal Stones

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