Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment

<p>Band selectivity to address specific resonances in a spectrum enables one to encode individual settings for diffusion experiments. In a single experiment, this could include different gradient strengths (enabling coverage of a larger range of diffusion constants), different diffusion delays...

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Autores principales:	N. MacKinnon, M. Alinaghian, P. Silva, T. Gloge, B. Luy, M. Jouda, J. G. Korvink
Formato:	article
Lenguaje:	EN
Publicado:	Copernicus Publications 2021
Materias:	Electricity and magnetism QC501-766
Acceso en línea:	https://doaj.org/article/c460f94f9bb349628fea93d5ba738903
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spelling	oai:doaj.org-article:c460f94f9bb349628fea93d5ba7389032021-11-19T13:35:11ZSelective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment10.5194/mr-2-835-20212699-0016https://doaj.org/article/c460f94f9bb349628fea93d5ba7389032021-11-01T00:00:00Zhttps://mr.copernicus.org/articles/2/835/2021/mr-2-835-2021.pdfhttps://doaj.org/toc/2699-0016<p>Band selectivity to address specific resonances in a spectrum enables one to encode individual settings for diffusion experiments. In a single experiment, this could include different gradient strengths (enabling coverage of a larger range of diffusion constants), different diffusion delays, or different gradient directions (enabling anisotropic diffusion measurement). In this report, a selective variant of the bipolar pulsed gradient eddy current delay (BPP-LED) experiment, enabling selective encoding of three resonances, was implemented. As proof of principle, the diffusion encoding gradient amplitude was assigned a range dependent on the selected signal, thereby allowing the extraction of the diffusion coefficient for water and a tripeptide (Met-Ala-Ser) with optimal settings in a single experiment.</p>N. MacKinnonM. AlinaghianP. SilvaP. SilvaT. GlogeB. LuyM. JoudaJ. G. KorvinkCopernicus PublicationsarticleElectricity and magnetismQC501-766ENMagnetic Resonance, Vol 2, Pp 835-842 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Electricity and magnetism QC501-766
spellingShingle	Electricity and magnetism QC501-766 N. MacKinnon M. Alinaghian P. Silva P. Silva T. Gloge B. Luy M. Jouda J. G. Korvink Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
description	<p>Band selectivity to address specific resonances in a spectrum enables one to encode individual settings for diffusion experiments. In a single experiment, this could include different gradient strengths (enabling coverage of a larger range of diffusion constants), different diffusion delays, or different gradient directions (enabling anisotropic diffusion measurement). In this report, a selective variant of the bipolar pulsed gradient eddy current delay (BPP-LED) experiment, enabling selective encoding of three resonances, was implemented. As proof of principle, the diffusion encoding gradient amplitude was assigned a range dependent on the selected signal, thereby allowing the extraction of the diffusion coefficient for water and a tripeptide (Met-Ala-Ser) with optimal settings in a single experiment.</p>
format	article
author	N. MacKinnon M. Alinaghian P. Silva P. Silva T. Gloge B. Luy M. Jouda J. G. Korvink
author_facet	N. MacKinnon M. Alinaghian P. Silva P. Silva T. Gloge B. Luy M. Jouda J. G. Korvink
author_sort	N. MacKinnon
title	Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
title_short	Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
title_full	Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
title_fullStr	Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
title_full_unstemmed	Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
title_sort	selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment
publisher	Copernicus Publications
publishDate	2021
url	https://doaj.org/article/c460f94f9bb349628fea93d5ba738903
work_keys_str_mv	AT nmackinnon selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT malinaghian selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT psilva selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT psilva selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT tgloge selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT bluy selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT mjouda selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment AT jgkorvink selectiveexcitationenablesencodingandmeasurementofmultiplediffusionparametersinasingleexperiment
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Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment

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