Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]

Tai Y, Zhang LH, Gao JH, et al. Cancer Manag Res. 2019;11:2831–2848. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 7A on page 2842 is incorrect. The correct Figure 7 is shown in Download Article. Figure 7 Celecoxib up-regulated...

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Autores principales:	Tai Y, Zhang LH, Gao JH, Zhao C, Tong H, Ye C, Huang ZY, Liu R, Tang CW
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	cyclooxygenase-2 hepatocellular carcinoma celecoxib survival Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/c4641c9fe6114ea2b44845c19f49d780
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spelling	oai:doaj.org-article:c4641c9fe6114ea2b44845c19f49d7802021-11-07T18:42:56ZSuppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]1179-1322https://doaj.org/article/c4641c9fe6114ea2b44845c19f49d7802021-11-01T00:00:00Zhttps://www.dovepress.com/corrigendum-suppressing-growth-and-invasion-of-human-hepatocellular-ca-peer-reviewed-fulltext-article-CMARhttps://doaj.org/toc/1179-1322Tai Y, Zhang LH, Gao JH, et al. Cancer Manag Res. 2019;11:2831–2848. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 7A on page 2842 is incorrect. The correct Figure 7 is shown in Download Article. Figure 7 Celecoxib up-regulated E-cadherin via inhibition of COX-2–PGE2–EP2–p-Akt/p-ERK in Bel7402 cells. Compared with DMSO-treated and empty plasmid-transfected Bel7402 cells, overexpression of COX-2 by using COX-2 ORF plasmid induced reduction of E-cadherin expression and increase of p-Akt and p-ERK expression determined by IF (A) and Western blot (D). Compared with DMSO-treated cells, the expression of E-cadherin quantified by IF (B and C) and Western blot (E and F) was upregulated by EP2 inhibitor AH6809, Akt inhibitor MK2206, and ERK inhibitor AZD6244, but down-regulated by PGE2, which could be reversed by AH6809. Meanwhile, the expression of p-Akt and p-ERK was significantly suppressed by treatment with celecoxib and AH6809 but was enhanced by treatment with PGE2, which could be inhibited by AH6809 (E). Scale bar =50 μm for IF. The authors apologize for these errors and advise they do not affect the interpretation of data or the conclusion of the study. Read the original articleTai YZhang LHGao JHZhao CTong HYe CHuang ZYLiu RTang CWDove Medical Pressarticlecyclooxygenase-2hepatocellular carcinomacelecoxibsurvivalNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancer Management and Research, Vol Volume 13, Pp 8353-8354 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cyclooxygenase-2 hepatocellular carcinoma celecoxib survival Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	cyclooxygenase-2 hepatocellular carcinoma celecoxib survival Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Tai Y Zhang LH Gao JH Zhao C Tong H Ye C Huang ZY Liu R Tang CW Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]
description	Tai Y, Zhang LH, Gao JH, et al. Cancer Manag Res. 2019;11:2831–2848. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 7A on page 2842 is incorrect. The correct Figure 7 is shown in Download Article. Figure 7 Celecoxib up-regulated E-cadherin via inhibition of COX-2–PGE2–EP2–p-Akt/p-ERK in Bel7402 cells. Compared with DMSO-treated and empty plasmid-transfected Bel7402 cells, overexpression of COX-2 by using COX-2 ORF plasmid induced reduction of E-cadherin expression and increase of p-Akt and p-ERK expression determined by IF (A) and Western blot (D). Compared with DMSO-treated cells, the expression of E-cadherin quantified by IF (B and C) and Western blot (E and F) was upregulated by EP2 inhibitor AH6809, Akt inhibitor MK2206, and ERK inhibitor AZD6244, but down-regulated by PGE2, which could be reversed by AH6809. Meanwhile, the expression of p-Akt and p-ERK was significantly suppressed by treatment with celecoxib and AH6809 but was enhanced by treatment with PGE2, which could be inhibited by AH6809 (E). Scale bar =50 μm for IF. The authors apologize for these errors and advise they do not affect the interpretation of data or the conclusion of the study. Read the original article
format	article
author	Tai Y Zhang LH Gao JH Zhao C Tong H Ye C Huang ZY Liu R Tang CW
author_facet	Tai Y Zhang LH Gao JH Zhao C Tong H Ye C Huang ZY Liu R Tang CW
author_sort	Tai Y
title	Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]
title_short	Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]
title_full	Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]
title_fullStr	Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]
title_full_unstemmed	Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]
title_sort	suppressing growth and invasion of human hepatocellular carcinoma cells by celecoxib through inhibition of cyclooxygenase-2 [corrigendum]
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/c4641c9fe6114ea2b44845c19f49d780
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Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]

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