Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil

Background: Free radicals that enter the body due to consumption of reused cooking oil can cause liver cell damage. Mangosteen peel extract (Garcinia mangostana L) is known to contain mangostin as an ntioxidant. However, it is not known whether it can repair liver damage. Objective: To deter mine t...

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Autores principales:	Esti Widyastuti, Nani Maharani, Astika Widy Utomo
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Sultan Agung Semarang 2018
Materias:	used cooking oil mangosteen peel extract sgot levels sgpt levels Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c471732ddbf946349511291a70790e2e
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spelling	oai:doaj.org-article:c471732ddbf946349511291a70790e2e2021-11-25T13:16:08ZEffect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil2085-15452339-093X10.30659/sainsmed.v9i2.2286https://doaj.org/article/c471732ddbf946349511291a70790e2e2018-09-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/2286https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XBackground: Free radicals that enter the body due to consumption of reused cooking oil can cause liver cell damage. Mangosteen peel extract (Garcinia mangostana L) is known to contain mangostin as an ntioxidant. However, it is not known whether it can repair liver damage. Objective: To deter mine the ef fect of mangosteen peel extract on the levels of SGOT and SGPT of Wistar rats fed with reused cooking oil.the ef fect of mangosteen peel extract on the levels of SGOT and SGPT of Wistar rats fed with reused cooking oil. Methods: This study was a tr ue experimental study with post-test only controlled group design. Twenty four male Wistar rats were randomly divided into 4 groups randomly. The CN-G group was given the standard diet, the MJ-G group was given a standard diet and cooking oil, the MJM- 400 group was given standard diet, reused cooking oil, and mangosteen peel extract at a dose of 400 mg/KgBW, and the MJM-800 group was fed with a standard, reused cooking oil, and mangosteen peel extract at 800mg/KgBW. The treatment was car ried out for 28 days, and then continued with examination of reused cooking oil, and mangosteen peel extract at 800mg/KgBW. The treatment was car ried out for 28 days, and then continued with examination of SGOT and SGPT levels using the Inter national Federation of Clinical Chemistr y (IFCC) method without Pyridoxal Phosphate 37ºC. Results: Kr uskal Walis test showed that SGOT and SGPT levels showed no signif icant dif ferences between groups (p = 0.197 and 0.063, respectively). Conclusion: administration of mangosteen (Garcinia mangostana L) peel extract did not af fect SGOT levels, even tended to increase SGPT levels in rats induced by cooking oil.Esti WidyastutiNani MaharaniAstika Widy UtomoUniversitas Sultan Agung Semarangarticleused cooking oilmangosteen peel extractsgot levelssgpt levelsMedicine (General)R5-920ENSains Medika, Vol 9, Iss 2, Pp 45-49 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	used cooking oil mangosteen peel extract sgot levels sgpt levels Medicine (General) R5-920
spellingShingle	used cooking oil mangosteen peel extract sgot levels sgpt levels Medicine (General) R5-920 Esti Widyastuti Nani Maharani Astika Widy Utomo Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil
description	Background: Free radicals that enter the body due to consumption of reused cooking oil can cause liver cell damage. Mangosteen peel extract (Garcinia mangostana L) is known to contain mangostin as an ntioxidant. However, it is not known whether it can repair liver damage. Objective: To deter mine the ef fect of mangosteen peel extract on the levels of SGOT and SGPT of Wistar rats fed with reused cooking oil.the ef fect of mangosteen peel extract on the levels of SGOT and SGPT of Wistar rats fed with reused cooking oil. Methods: This study was a tr ue experimental study with post-test only controlled group design. Twenty four male Wistar rats were randomly divided into 4 groups randomly. The CN-G group was given the standard diet, the MJ-G group was given a standard diet and cooking oil, the MJM- 400 group was given standard diet, reused cooking oil, and mangosteen peel extract at a dose of 400 mg/KgBW, and the MJM-800 group was fed with a standard, reused cooking oil, and mangosteen peel extract at 800mg/KgBW. The treatment was car ried out for 28 days, and then continued with examination of reused cooking oil, and mangosteen peel extract at 800mg/KgBW. The treatment was car ried out for 28 days, and then continued with examination of SGOT and SGPT levels using the Inter national Federation of Clinical Chemistr y (IFCC) method without Pyridoxal Phosphate 37ºC. Results: Kr uskal Walis test showed that SGOT and SGPT levels showed no signif icant dif ferences between groups (p = 0.197 and 0.063, respectively). Conclusion: administration of mangosteen (Garcinia mangostana L) peel extract did not af fect SGOT levels, even tended to increase SGPT levels in rats induced by cooking oil.
format	article
author	Esti Widyastuti Nani Maharani Astika Widy Utomo
author_facet	Esti Widyastuti Nani Maharani Astika Widy Utomo
author_sort	Esti Widyastuti
title	Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil
title_short	Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil
title_full	Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil
title_fullStr	Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil
title_full_unstemmed	Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil
title_sort	effect of mangosteen peel extract on sgot and sgpt in rats fed reused cooking oil
publisher	Universitas Sultan Agung Semarang
publishDate	2018
url	https://doaj.org/article/c471732ddbf946349511291a70790e2e
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Effect of Mangosteen Peel Extract on SGOT and SGPT in Rats Fed Reused Cooking Oil

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