Expert opinion on the management of hepatitis C infection in Kuwait

Motaz Fathy Saad,1 Saleh Alenezi,2 Haifaa Asker3 On behalf of the Kuwait Hepatology Club 1Haya Al-Habib Gastroenterology and Hepatology Center, Mubarak Alkabir Hospital, Hawaly, Kuwait; 2Unit of Gastroenterology and Hepatology, Department of Medicine, Farwaniya Hospital, Kuwait City, Kuwait; 3Thunay...

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Autores principales: Saad MF, Alenezi S, Asker H
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Publicado: Dove Medical Press 2018
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spelling oai:doaj.org-article:c47e19e751c8417ca14fc05a3d084f992021-12-02T05:17:49ZExpert opinion on the management of hepatitis C infection in Kuwait1179-1535https://doaj.org/article/c47e19e751c8417ca14fc05a3d084f992018-09-01T00:00:00Zhttps://www.dovepress.com/expert-opinion-on-the-management-of-hepatitis-c-infection-in-kuwait-peer-reviewed-article-HMERhttps://doaj.org/toc/1179-1535Motaz Fathy Saad,1 Saleh Alenezi,2 Haifaa Asker3 On behalf of the Kuwait Hepatology Club 1Haya Al-Habib Gastroenterology and Hepatology Center, Mubarak Alkabir Hospital, Hawaly, Kuwait; 2Unit of Gastroenterology and Hepatology, Department of Medicine, Farwaniya Hospital, Kuwait City, Kuwait; 3Thunayan Al-Ghanim Gastroenterology and Hepatology Center, Al-Amiri Hospital, Kuwait City, Kuwait Abstract: Chronic hepatitis C virus (HCV) infection is a leading cause of death, especially in immunocompromised patients. The lack of clear prevalence data in the Middle East makes it difficult to estimate the true morbidity and mortality burden of HCV. In Kuwait, estimating the burden of disease is complicated by the constant flow of expatriates, many of whom are from HCV-endemic areas. The development of new and revolutionary treatments for HCV necessitates the standardization of clinical practice across all healthcare institutions. While international guidelines from the American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of the Liver (EASL) do address this evolving treatment landscape, the cost-driven treatment prioritization of patients by these guidelines and unique HCV genotype presentation in the Kuwaiti population prompted the development of a more tailored approach. The predominant HCV genotypes prevalent in Kuwait are genotypes 4 and 1. The Kuwait Hepatology Club (KHC), comprising hepatologists across all major institutions in Kuwait, conducted several consensus meetings to develop the scoring criteria, evaluate all current evidence, and propose screening, diagnosis, and treatment suggestions for the management of HCV in this population. While these treatment suggestions were largely consistent with the 2016 AASLD and 2015 EASL guidelines, they also addressed gaps in the unmet needs of the Kuwaiti population with HCV. Keywords: hepatitis C, diagnosis, treatment, management, KuwaitSaad MFAlenezi SAsker HDove Medical PressarticleHepatitis CdiagnosistreatmentmanagementKuwaitDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol Volume 10, Pp 117-132 (2018)
institution DOAJ
collection DOAJ
language EN
topic Hepatitis C
diagnosis
treatment
management
Kuwait
Diseases of the digestive system. Gastroenterology
RC799-869
spellingShingle Hepatitis C
diagnosis
treatment
management
Kuwait
Diseases of the digestive system. Gastroenterology
RC799-869
Saad MF
Alenezi S
Asker H
Expert opinion on the management of hepatitis C infection in Kuwait
description Motaz Fathy Saad,1 Saleh Alenezi,2 Haifaa Asker3 On behalf of the Kuwait Hepatology Club 1Haya Al-Habib Gastroenterology and Hepatology Center, Mubarak Alkabir Hospital, Hawaly, Kuwait; 2Unit of Gastroenterology and Hepatology, Department of Medicine, Farwaniya Hospital, Kuwait City, Kuwait; 3Thunayan Al-Ghanim Gastroenterology and Hepatology Center, Al-Amiri Hospital, Kuwait City, Kuwait Abstract: Chronic hepatitis C virus (HCV) infection is a leading cause of death, especially in immunocompromised patients. The lack of clear prevalence data in the Middle East makes it difficult to estimate the true morbidity and mortality burden of HCV. In Kuwait, estimating the burden of disease is complicated by the constant flow of expatriates, many of whom are from HCV-endemic areas. The development of new and revolutionary treatments for HCV necessitates the standardization of clinical practice across all healthcare institutions. While international guidelines from the American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of the Liver (EASL) do address this evolving treatment landscape, the cost-driven treatment prioritization of patients by these guidelines and unique HCV genotype presentation in the Kuwaiti population prompted the development of a more tailored approach. The predominant HCV genotypes prevalent in Kuwait are genotypes 4 and 1. The Kuwait Hepatology Club (KHC), comprising hepatologists across all major institutions in Kuwait, conducted several consensus meetings to develop the scoring criteria, evaluate all current evidence, and propose screening, diagnosis, and treatment suggestions for the management of HCV in this population. While these treatment suggestions were largely consistent with the 2016 AASLD and 2015 EASL guidelines, they also addressed gaps in the unmet needs of the Kuwaiti population with HCV. Keywords: hepatitis C, diagnosis, treatment, management, Kuwait
format article
author Saad MF
Alenezi S
Asker H
author_facet Saad MF
Alenezi S
Asker H
author_sort Saad MF
title Expert opinion on the management of hepatitis C infection in Kuwait
title_short Expert opinion on the management of hepatitis C infection in Kuwait
title_full Expert opinion on the management of hepatitis C infection in Kuwait
title_fullStr Expert opinion on the management of hepatitis C infection in Kuwait
title_full_unstemmed Expert opinion on the management of hepatitis C infection in Kuwait
title_sort expert opinion on the management of hepatitis c infection in kuwait
publisher Dove Medical Press
publishDate 2018
url https://doaj.org/article/c47e19e751c8417ca14fc05a3d084f99
work_keys_str_mv AT saadmf expertopiniononthemanagementofhepatitiscinfectioninkuwait
AT alenezis expertopiniononthemanagementofhepatitiscinfectioninkuwait
AT askerh expertopiniononthemanagementofhepatitiscinfectioninkuwait
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