Bimatoprost in the treatment of eyelash hypotrichosis

Simon K LawJules Stein Eye Institute, University of California, Los Angeles, California, USAAbstract: Eyelashes hypotrichosis is a condition indicated by an inadequate amount of eyelashes. Hypertrichosis of eyelashes, characterized by excessive eyelash growth, is a regular phenomenon associated with...

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Autor principal:	Simon K Law
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/c47f45537f0a4844befa92c2fb1fa8d1
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spelling	oai:doaj.org-article:c47f45537f0a4844befa92c2fb1fa8d12021-12-02T06:56:25ZBimatoprost in the treatment of eyelash hypotrichosis1177-54671177-5483https://doaj.org/article/c47f45537f0a4844befa92c2fb1fa8d12010-04-01T00:00:00Zhttp://www.dovepress.com/bimatoprost-in-the-treatment-of-eyelash-hypotrichosis-a4299https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Simon K LawJules Stein Eye Institute, University of California, Los Angeles, California, USAAbstract: Eyelashes hypotrichosis is a condition indicated by an inadequate amount of eyelashes. Hypertrichosis of eyelashes, characterized by excessive eyelash growth, is a regular phenomenon associated with ophthalmic prostaglandin and prostamide analogs. Recently, the US Food and Drug Administration approved Latisse&reg; (bimatoprost 0.03% solution), identical to the ophthalmic solution for glaucoma treatment, for increasing eyelash length, thickness and darkness in patients with hypotrichosis of the eyelashes. When prostaglandin and prostamide analogs interact with the prostanoid receptors in the hair follicle, this most likely stimulates the resting follicles (telogen phase) to growing follicles (anagen phase). Prostaglandin and prostamide analogs may also prolong the anagen phase of eyelashes, leading to an increase of eyelash length. Although bimatoprost is effective in promoting increased growth of healthy eyelashes and adnexal hairs, its effectiveness in patients with eyelash alopecia areata is debatable and its protective effect is not yet studied in patients with eyelash loss secondary to radiation or chemotherapy. Bimatoprost is generally safe when applied to the base of the eyelashes at the lid margin with minimum side effects. However, other ocular or systemic side effects associated with ophthalmic prostaglandin and prostamide analogs may occur when instilled on the surface of the eye, and patients must be informed and monitored.Keywords: bimatoprost, Latisse, prostaglandin, prostamide, eyelash, hypotrichosis Simon K LawDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 349-358 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Simon K Law Bimatoprost in the treatment of eyelash hypotrichosis
description	Simon K LawJules Stein Eye Institute, University of California, Los Angeles, California, USAAbstract: Eyelashes hypotrichosis is a condition indicated by an inadequate amount of eyelashes. Hypertrichosis of eyelashes, characterized by excessive eyelash growth, is a regular phenomenon associated with ophthalmic prostaglandin and prostamide analogs. Recently, the US Food and Drug Administration approved Latisse&reg; (bimatoprost 0.03% solution), identical to the ophthalmic solution for glaucoma treatment, for increasing eyelash length, thickness and darkness in patients with hypotrichosis of the eyelashes. When prostaglandin and prostamide analogs interact with the prostanoid receptors in the hair follicle, this most likely stimulates the resting follicles (telogen phase) to growing follicles (anagen phase). Prostaglandin and prostamide analogs may also prolong the anagen phase of eyelashes, leading to an increase of eyelash length. Although bimatoprost is effective in promoting increased growth of healthy eyelashes and adnexal hairs, its effectiveness in patients with eyelash alopecia areata is debatable and its protective effect is not yet studied in patients with eyelash loss secondary to radiation or chemotherapy. Bimatoprost is generally safe when applied to the base of the eyelashes at the lid margin with minimum side effects. However, other ocular or systemic side effects associated with ophthalmic prostaglandin and prostamide analogs may occur when instilled on the surface of the eye, and patients must be informed and monitored.Keywords: bimatoprost, Latisse, prostaglandin, prostamide, eyelash, hypotrichosis
format	article
author	Simon K Law
author_facet	Simon K Law
author_sort	Simon K Law
title	Bimatoprost in the treatment of eyelash hypotrichosis
title_short	Bimatoprost in the treatment of eyelash hypotrichosis
title_full	Bimatoprost in the treatment of eyelash hypotrichosis
title_fullStr	Bimatoprost in the treatment of eyelash hypotrichosis
title_full_unstemmed	Bimatoprost in the treatment of eyelash hypotrichosis
title_sort	bimatoprost in the treatment of eyelash hypotrichosis
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/c47f45537f0a4844befa92c2fb1fa8d1
work_keys_str_mv	AT simonklaw bimatoprostinthetreatmentofeyelashhypotrichosis
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Bimatoprost in the treatment of eyelash hypotrichosis

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