Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

Here, the authors compare seven low passage Zika virus (ZIKV) strains representing the recently circulating viral genetic diversity of African and Asian strains and find that African ZIKV strains have higher transmissibility in mosquitoes and higher lethality in both adult and fetal mice.

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Autores principales: Fabien Aubry, Sofie Jacobs, Maïlis Darmuzey, Sebastian Lequime, Leen Delang, Albin Fontaine, Natapong Jupatanakul, Elliott F. Miot, Stéphanie Dabo, Caroline Manet, Xavier Montagutelli, Artem Baidaliuk, Fabiana Gámbaro, Etienne Simon-Lorière, Maxime Gilsoul, Claudia M. Romero-Vivas, Van-Mai Cao-Lormeau, Richard G. Jarman, Cheikh T. Diagne, Oumar Faye, Ousmane Faye, Amadou A. Sall, Johan Neyts, Laurent Nguyen, Suzanne J. F. Kaptein, Louis Lambrechts
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c48f91d15fcb42c39e43fb6ac7859613
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spelling oai:doaj.org-article:c48f91d15fcb42c39e43fb6ac78596132021-12-02T14:11:09ZRecent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains10.1038/s41467-021-21199-z2041-1723https://doaj.org/article/c48f91d15fcb42c39e43fb6ac78596132021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21199-zhttps://doaj.org/toc/2041-1723Here, the authors compare seven low passage Zika virus (ZIKV) strains representing the recently circulating viral genetic diversity of African and Asian strains and find that African ZIKV strains have higher transmissibility in mosquitoes and higher lethality in both adult and fetal mice.Fabien AubrySofie JacobsMaïlis DarmuzeySebastian LequimeLeen DelangAlbin FontaineNatapong JupatanakulElliott F. MiotStéphanie DaboCaroline ManetXavier MontagutelliArtem BaidaliukFabiana GámbaroEtienne Simon-LorièreMaxime GilsoulClaudia M. Romero-VivasVan-Mai Cao-LormeauRichard G. JarmanCheikh T. DiagneOumar FayeOusmane FayeAmadou A. SallJohan NeytsLaurent NguyenSuzanne J. F. KapteinLouis LambrechtsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fabien Aubry
Sofie Jacobs
Maïlis Darmuzey
Sebastian Lequime
Leen Delang
Albin Fontaine
Natapong Jupatanakul
Elliott F. Miot
Stéphanie Dabo
Caroline Manet
Xavier Montagutelli
Artem Baidaliuk
Fabiana Gámbaro
Etienne Simon-Lorière
Maxime Gilsoul
Claudia M. Romero-Vivas
Van-Mai Cao-Lormeau
Richard G. Jarman
Cheikh T. Diagne
Oumar Faye
Ousmane Faye
Amadou A. Sall
Johan Neyts
Laurent Nguyen
Suzanne J. F. Kaptein
Louis Lambrechts
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
description Here, the authors compare seven low passage Zika virus (ZIKV) strains representing the recently circulating viral genetic diversity of African and Asian strains and find that African ZIKV strains have higher transmissibility in mosquitoes and higher lethality in both adult and fetal mice.
format article
author Fabien Aubry
Sofie Jacobs
Maïlis Darmuzey
Sebastian Lequime
Leen Delang
Albin Fontaine
Natapong Jupatanakul
Elliott F. Miot
Stéphanie Dabo
Caroline Manet
Xavier Montagutelli
Artem Baidaliuk
Fabiana Gámbaro
Etienne Simon-Lorière
Maxime Gilsoul
Claudia M. Romero-Vivas
Van-Mai Cao-Lormeau
Richard G. Jarman
Cheikh T. Diagne
Oumar Faye
Ousmane Faye
Amadou A. Sall
Johan Neyts
Laurent Nguyen
Suzanne J. F. Kaptein
Louis Lambrechts
author_facet Fabien Aubry
Sofie Jacobs
Maïlis Darmuzey
Sebastian Lequime
Leen Delang
Albin Fontaine
Natapong Jupatanakul
Elliott F. Miot
Stéphanie Dabo
Caroline Manet
Xavier Montagutelli
Artem Baidaliuk
Fabiana Gámbaro
Etienne Simon-Lorière
Maxime Gilsoul
Claudia M. Romero-Vivas
Van-Mai Cao-Lormeau
Richard G. Jarman
Cheikh T. Diagne
Oumar Faye
Ousmane Faye
Amadou A. Sall
Johan Neyts
Laurent Nguyen
Suzanne J. F. Kaptein
Louis Lambrechts
author_sort Fabien Aubry
title Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
title_short Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
title_full Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
title_fullStr Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
title_full_unstemmed Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
title_sort recent african strains of zika virus display higher transmissibility and fetal pathogenicity than asian strains
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c48f91d15fcb42c39e43fb6ac7859613
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